Evidence map›Paper›PMID 32802433›Full record

ArticleJournal of thoracic disease2020

Efficacy and safety of airway stenting to treat anastomotic complications after lung transplant: a cohort study.

Kevin C Ma, Mingyang Li, Andrew R Haas, Anthony R Lanfranco, Edmund K Moon, David M DiBardino

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Three Decades Single Center Experience of Airway Complications After Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kevin C MaSection of Interventional Pulmonology, Division of Pulmonary, Allergy, & Critical Care, University of Pennsylvania, Philadelphia, PA, USA.
Mingyang LiDepartments of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USA.
Andrew R HaasSection of Interventional Pulmonology, Division of Pulmonary, Allergy, & Critical Care, University of Pennsylvania, Philadelphia, PA, USA.
Anthony R LanfrancoSection of Interventional Pulmonology, Division of Pulmonary, Allergy, & Critical Care, University of Pennsylvania, Philadelphia, PA, USA.
Edmund K MoonSection of Interventional Pulmonology, Division of Pulmonary, Allergy, & Critical Care, University of Pennsylvania, Philadelphia, PA, USA.
David M DiBardinoSection of Interventional Pulmonology, Division of Pulmonary, Allergy, & Critical Care, University of Pennsylvania, Philadelphia, PA, USA.
University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAirway complications affect roughly 15-20% of lung transplant patients. Airway stents are an attractive therapeutic option; however, no experimental or controlled observational data exists to draw firm conclusions regarding airway stent efficacy and safety in this population.

methodsWe performed a retrospective cohort study of patients who underwent airway stent placement for post-transplant anastomotic airway complications. The primary outcomes were improvements in FEV1 and reduction in bronchoscopies post-stent.

resultsWe identified 36 patients who underwent airway stenting between October 2012 and October 2017. A total of 47 airways underwent stent placement. Improvement in FEV1 after stent placement was only observed in patients who ultimately were able to undergo stent removal. Patients who expired prior to stent removal had no immediate FEV1 improvement after stent placement. Among subjects who underwent stent removal, there was a statistically significant reduction in number of bronchoscopies per month after stent removal compared to pre-stent placement. Male gender was the only predictor of FEV1 improvement after stent placement while male gender and dehiscence prior to stent placement predicted increased number of bronchoscopies after stent placement. Mucous plugging and granulation tissue formation were the most common stent related complications.

conclusionsOnly select patients benefit from stent placement for airways stenosis after lung transplant. Complications related to stent placement are common. Patients with airway complications treated with airway stents undergo a high volume of repeat procedures.

Indexed as

bronchoscopyLung transplantationself expandable metallic stents

Identifiers

PMID32802433
PMCPMC7399444
OpenAlexW3040131862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.