Evidence map›Paper›PMID 32802302›Full record

ReviewJournal of healthcare engineering2020

Network Meta-Analysis of the Safety of Drug Therapy for Cardiogenic Shock.

Xianyong Liao, Lin Qian, Song Zhang, Xiang Chen, Jing Lei

Open access · hybridAbstract readReviewNetwork Meta-Analysis
In one paragraph

Review in Journal of healthcare engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xianyong LiaoHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Lin QianHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Song ZhangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.ORCID 0000-0002-3919-3853
Xiang ChenHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jing LeiHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: (1) To conduct a network meta-analysis of clinical drugs used for cardiogenic shock and (2) provide evidence for the selection of medication for the treatment of this condition. Methods: PubMed, EMBASE, Cochrane library, China HowNet (CNKI), Wanfang database, and Weipu database were searched using keywords Dopamine, Dobutamine, Epinephrine, Adrenaline, Norepinephrine, Noradrenaline, Milrinone, Natriuretic peptide, Recombinant human brain natriuretic peptide, Levosimendan, Cardiac shock, and Cardiogenic shock. We select literature according to prespecified inclusion and exclusion criteria and record data such as drug type, mortality, and adverse reactions. Results: Twenty-eight of 1387 articles met inclusion criteria, comprising 1806 patients who suffered from cardiogenic shock. Dopamine, dobutamine, epinephrine, norepinephrine, milrinone, recombinant human brain natriuretic peptide, and levosimendan were all commonly used in the treatment of cardiogenic shock. Milrinone was most effective at reducing mortality and had the lowest incidence of adverse reactions. Conclusion: This network meta-analysis demonstrated that milrinone was the most effective medication at reducing mortality and adverse events in patients suffering from cardiogenic shock.

Indexed as

Patient SafetyTreatment OutcomeAgedDisease ProgressionDobutamineDopamineEpinephrineFemaleHemodynamicsHumansMaleMiddle AgedMilrinoneNatriuretic Peptide, BrainNorepinephrineRecombinant ProteinsDobutamineDopamineEpinephrineMilrinoneNatriuretic Peptide, BrainNorepinephrineRecombinant ProteinsSimendan

Identifiers

PMID32802302
PMCPMC7416258
OpenAlexW3046746201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.