Evidence map›Paper›PMID 32802273›Full record

ReviewComputational and structural biotechnology journal2020

Computational advances of tumor marker selection and sample classification in cancer proteomics.

Jing Tang, Yunxia Wang, Yongchao Luo, Jianbo Fu, Yang Zhang, Yi Li, Ziyu Xiao, Yan Lou, Yunqing Qiu, Feng Zhu

Open access · goldAbstract readReview
In one paragraph

Review in Computational and structural biotechnology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 44 citations in OpenAlex.

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  16. Development and evaluation of a radiomics model of restingAnnals of translational medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jing TangDepartment of Bioinformatics, Chongqing Medical University, Chongqing 400016, China.
Yunxia WangCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Yongchao LuoCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Jianbo FuCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Yang ZhangCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Yi LiCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Ziyu XiaoCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Yan LouZhejiang Provincial Key Laboratory for Drug Clinical Research and Evaluation, The First Affiliated Hospital, Zhejiang University, Hangzhou 310000, China.
Yunqing QiuZhejiang Provincial Key Laboratory for Drug Clinical Research and Evaluation, The First Affiliated Hospital, Zhejiang University, Hangzhou 310000, China.
Feng ZhuDepartment of Bioinformatics, Chongqing Medical University, Chongqing 400016, China.
Zhejiang University · CNFirst Affiliated Hospital Zhejiang University · CNChongqing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer proteomics has become a powerful technique for characterizing the protein markers driving transformation of malignancy, tracing proteome variation triggered by therapeutics, and discovering the novel targets and drugs for the treatment of oncologic diseases. To facilitate cancer diagnosis/prognosis and accelerate drug target discovery, a variety of methods for tumor marker identification and sample classification have been developed and successfully applied to cancer proteomic studies. This review article describes the most recent advances in those various approaches together with their current applications in cancer-related studies. Firstly, a number of popular feature selection methods are overviewed with objective evaluation on their advantages and disadvantages. Secondly, these methods are grouped into three major classes based on their underlying algorithms. Finally, a variety of sample separation algorithms are discussed. This review provides a comprehensive overview of the advances on tumor maker identification and patients/samples/tissues separations, which could be guidance to the researches in cancer proteomics.

Indexed as

ANN, Artificial Neural NetworkANOVA, Analysis of VarianceCancer proteomicsCFS, Correlation-based Feature SelectionComputational methodsDAPC, Discriminant Analysis of Principal ComponentDT, Decision TreesEDA, Estimation of Distribution AlgorithmFC, Fold ChangeGA, Genetic AlgorithmsGR, Gain RatioHCA, Hierarchical Cluster AnalysisHC, Hill ClimbingIG, Information GainLDA, Linear Discriminant AnalysisLIMMA, Linear Models for Microarray DataMBF, Markov Blanket FilterMWW, Mann–Whitney–Wilcoxon testOPLS-DA, Orthogonal Partial Least Squares Discriminant AnalysisPCA, Principal Component AnalysisPLS-DA, Partial Least Square Discriminant AnalysisRF, Random ForestRF-RFE, Random Forest with Recursive Feature EliminationSample classificationSAM, Significance Analysis of MicroarraysSA, Simulated AnnealingSBE, Sequential Backward EliminationSFS, and Sequential Forward SelectionSOM, Self-organizing MapsPLSDA, Sparse Partial Least Squares Discriminant AnalysisSU, Symmetrical UncertaintySVM-RFE, Support Vector Machine with Recursive Feature EliminationSVM, Support Vector Machinet-SNE, Student t DistributionTumor marker selectionχ2, Chi-square

Identifiers

PMID32802273
PMCPMC7403885
OpenAlexW3042285114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.