Evidence map›Paper›PMID 32802261›Full record

ArticleOxidative medicine and cellular longevity2020

Antioxidant Solution in Combination with Angiotensin-(1-7) Provides Myocardial Protection in Langendorff-Perfused Rat Hearts.

Michaela Andrä, Miriam Russ, Susanne Jauk, Mariana Lamacie, Ingrid Lang, Robert Arnold, Iva Brcic, Robson Santos, Reinhold Wintersteiger, Astrid Ortner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michaela AndräDepartment of Cardio-Thoracic and Vascular Surgery, Klinikum Klagenfurt am Wörthersee, 9020 Klagenfurt, Austria.ORCID https://orcid.org/0000-0003-2023-8991
Miriam RussInstitute of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, University of Graz, 8010 Graz, Austria.
Susanne JaukInstitute of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, University of Graz, 8010 Graz, Austria.
Mariana LamacieDepartment of Medicine, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada K1Y4W7.
Ingrid LangDivision of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, 8010 Graz, Austria.
Robert ArnoldGottfried Schatz Research Center-Biophysics, Medical University of Graz, 8010 Graz, Austria.ORCID https://orcid.org/0000-0002-0524-9812
Iva BrcicDiagnostic & Research Institute of Pathology, Medical University of Graz, 8010 Graz, Austria.
Robson SantosInstitute of Physiology, Laboratory of Hypertension, University of Minas Gerais, Belo Horizonte, MG 31270-901, Brazil.ORCID https://orcid.org/0000-0001-8738-5852
Reinhold WintersteigerInstitute of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, University of Graz, 8010 Graz, Austria.
Astrid OrtnerInstitute of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, University of Graz, 8010 Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As progressive organ shortage in cardiac transplantation demands extension of donor criteria, effort is needed to optimize graft survival. Reactive oxygen and nitrogen species, generated during organ procurement, transplantation, and reperfusion, contribute to acute and late graft dysfunction. The combined application of diverse substances acting via different molecular pathways appears to be a reasonable approach to face the complex mechanism of ischemia reperfusion injury. Thus, an antioxidant solution containing

Indexed as

Angiotensin IAnimalsAntioxidantsDisease Models, AnimalHeartMalePeptide FragmentsRatsAngiotensin Iangiotensin I (1-7)AntioxidantsPeptide Fragments

Identifiers

PMID32802261
PMCPMC7415103

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.