Evidence map›Paper›PMID 32802246›Full record

ArticleBayesian analysis2020

Bayesian Network Marker Selection via the Thresholded Graph Laplacian Gaussian Prior.

Qingpo Cai, Jian Kang, Tianwei Yu

Open access · diamondAbstract read
In one paragraph

Article in Bayesian analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Bayesian Spatial Blind Source Separation via the Thresholded Gaussian Process.Journal of the American Statistical Association · 2024
    Article
  3. Article
  4. Bayesian Inferences on Neural Activity in EEG-Based Brain-Computer Interface.Journal of the American Statistical Association · 2022
    Article
  5. Article
  6. Article
  7. Bayesian Sparse Mediation Analysis with Targeted Penalization of Natural Indirect Effects.Journal of the Royal Statistical Society. Series C, Applied statistics · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Qingpo CaiDepartment of Biostatistics and Bioinformatics, Emory University, Atlanta, GA 30322, USA.
Jian KangDepartment of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
Tianwei YuDepartment of Biostatistics and Bioinformatics, Emory University, Atlanta, GA 30322, USA.
Emory University · USUniversity of Michigan–Ann Arbor · US

Funding

Statistical ICA Methods for Analysis & Integration of Multi-dimensional Data Diversity SupplementR01MH105561 · NIMH · EMORY UNIVERSITY · PI GUO, YING, KANG, JIAN · 2014 to 2024
$4.3M
Bayesian Network Biomarker Selection in Metabolomics DataR01GM124061 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KANG, JIAN · 2017 to 2020
$1.4M
NIGMS NIH HHS R01 GM124061NIMH NIH HHS R01 MH105561
6 · The paper itself

Abstract

Selecting informative nodes over large-scale networks becomes increasingly important in many research areas. Most existing methods focus on the local network structure and incur heavy computational costs for the large-scale problem. In this work, we propose a novel prior model for Bayesian network marker selection in the generalized linear model (GLM) framework: the Thresholded Graph Laplacian Gaussian (TGLG) prior, which adopts the graph Laplacian matrix to characterize the conditional dependence between neighboring markers accounting for the global network structure. Under mild conditions, we show the proposed model enjoys the posterior consistency with a diverging number of edges and nodes in the network. We also develop a Metropolis-adjusted Langevin algorithm (MALA) for efficient posterior computation, which is scalable to large-scale networks. We illustrate the superiorities of the proposed method compared with existing alternatives via extensive simulation studies and an analysis of the breast cancer gene expression dataset in the Cancer Genome Atlas (TCGA).

Indexed as

gene networkgeneralized linear modelnetwork marker selectionposterior consistencythresholded graph Laplacian Gaussian prior

Identifiers

PMID32802246
PMCPMC7428197
OpenAlexW2893116636

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.