ArticleBeilstein journal of organic chemistry2020
Stereoselective Biginelli-like reaction catalyzed by a chiral phosphoric acid bearing two hydroxy groups.
Article in Beilstein journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Precision in stereochemistry: the integral role of catalytic asymmetric Biginelli reaction in crafting enantiomerically pure dihydropyrimidinones.Molecular diversity · 2024Review
- Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction.Molecules (Basel, Switzerland) · 2024Review
- Synthesis of 3,4-Dihydropyrimidin(thio)one Containing Scaffold: Biginelli-like Reactions.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis.ChemSusChem · 2021Review
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5 authors.
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Abstract
To develop new efficient stereoselective catalysts for Biginelli-like reactions, a chiral phosphoric acid bearing two hydroxy groups derived from ʟ-tartaric acid was successfully synthesized via highly regioselective transformations of enantiopure 1,1,4,4-tetraphenylbutanetetraol. The obtained catalyst effectively catalyzed Biginelli-like reactions with moderate to good enantioselectivities. Control experiments indicated that the presence of the two hydroxy groups were indispensable for achieving a high enantioselectivity.
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