Evidence map›Paper›PMID 32802191›Full record

ArticleTheranostics2020

Instability of circular RNAs in clinical tissue samples impairs their reliable expression analysis using RT-qPCR: from the myth of their advantage as biomarkers to reality.

Hannah Rochow, Antonia Franz, Monika Jung, Sabine Weickmann, Bernhard Ralla, Ergin Kilic, Carsten Stephan, Annika Fendler, Klaus Jung

Abstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. The Use of circRNAs as Biomarkers of Cancer.Methods in molecular biology (Clifton, N.J.) · 2021
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hannah RochowDepartment of Urology, Charité - University Medicine, 10117 Berlin, Germany.
Antonia FranzDepartment of Urology, Charité - University Medicine, 10117 Berlin, Germany.
Monika JungDepartment of Urology, Charité - University Medicine, 10117 Berlin, Germany.
Sabine WeickmannDepartment of Urology, Charité - University Medicine, 10117 Berlin, Germany.
Bernhard RallaDepartment of Urology, Charité - University Medicine, 10117 Berlin, Germany.
Ergin KilicDepartment of Pathology, Charité - University Medicine, 10117 Berlin, Germany.
Carsten StephanDepartment of Urology, Charité - University Medicine, 10117 Berlin, Germany.
Annika FendlerBerlin Institute for Urologic Research, 10115 Berlin, Germany.
Klaus JungDepartment of Urology, Charité - University Medicine, 10117 Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkersCell LineCell Line, TumorGene Expression ProfilingHEK293 CellsHumansMicroRNAsReal-Time Polymerase Chain ReactionRNA, CircularRNA, MessengerBiomarkersMicroRNAsRNA, CircularRNA, MessengercircRNA stabilitycircular RNAsnormalizationRNA degradationRNA integrityRT-qPCR

Identifiers

PMID32802191
PMCPMC7415809

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.