Evidence map›Paper›PMID 32802189›Full record

ArticleTheranostics2020

Epigenetic repression of miR-17 contributed to di(2-ethylhexyl) phthalate-triggered insulin resistance by targeting Keap1-Nrf2/miR-200a axis in skeletal muscle.

Jie Wei, Qiongyu Hao, Chengkun Chen, Juan Li, Xikui Han, Zhao Lei, Tao Wang, Yinan Wang, Xiang You, Xiaoxuan Chen and 7 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Impact of 4-Environment & health (Washington, D.C.) · 2025
    Article
  7. Review
  8. The Effects of the Ethanol Extract ofJournal of experimental pharmacology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Phthalate and gallstones: the mediation of insulin.Frontiers in public health · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Critical Overview on Endocrine Disruptors in Diabetes Mellitus.International journal of molecular sciences · 2023
    Review
  18. Article
  19. Article
  20. Association of urinary phthalate metabolites with sarcopenia in US adults: NHANES 1999-2006.Environmental science and pollution research international · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Jie WeiDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Qiongyu HaoDivision of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, David Geffen UCLA School of Medicine, and UCLA Jonsson Comprehensive Cancer Center, 1748 E. 118th Street, Los Angeles, CA, 90059, USA.
Chengkun ChenDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Juan LiDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Xikui HanDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Zhao LeiState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.
Tao WangThe First Affiliated Hospital of Xiamen University, Xiamen, 361003, China.
Yinan WangDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Xiang YouDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Xiaoxuan ChenState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.
Huasheng LiDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Yuxin DingDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Weihao HuangDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Yangyang HuDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Shuirong LinDepartment of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen 361102, China.
Heqing ShenState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.
Yi LinState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.
Xiamen University · CNCharles R. Drew University of Medicine and Science · USFirst Affiliated Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell LineDiabetes Mellitus, Type 2Down-RegulationEpigenetic RepressionInsulinInsulin ResistanceKelch-Like ECH-Associated Protein 1MaleMiceMice, Inbred C57BLMicroRNAsMuscle, SkeletalNF-E2-Related Factor 2Oxidative StressPhthalic AcidsInsulinKeap1 protein, mouseKelch-Like ECH-Associated Protein 1MicroRNAsMirn17 microRNA, mouseMirn200 microRNA, mouseNfe2l2 protein, mouseNF-E2-Related Factor 2phthalic acidPhthalic AcidsEnvironmental endocrine-disrupting chemicalInsulin resistancemicroRNAOxidative stressSkeletal muscle

Identifiers

PMID32802189
PMCPMC7415800
OpenAlexW3045327256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.