Evidence map›Paper›PMID 32802178›Full record

ArticleTheranostics2020

Deubiquitinase USP7-mediated MCL-1 up-regulation enhances Arsenic and Benzo(a)pyrene co-exposure-induced Cancer Stem Cell-like property and Tumorigenesis.

Ping Yang, Jie Xie, Yunfei Li, Hsuan-Pei Lin, William Fenske, Marco Clementino, Yiguo Jiang, Chengfeng Yang, Zhishan Wang

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Up-regulation of RNA mToxicology and applied pharmacology · 2023
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Ping YangDepartment of Toxicology and Cancer Biology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Jie XieDepartment of Toxicology and Cancer Biology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Yunfei LiDepartment of Toxicology and Cancer Biology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Hsuan-Pei LinDepartment of Toxicology and Cancer Biology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
William FenskeDepartment of Toxicology and Cancer Biology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Marco ClementinoDepartment of Toxicology and Cancer Biology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Yiguo JiangSchool of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Chengfeng YangDepartment of Toxicology and Cancer Biology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Zhishan WangDepartment of Toxicology and Cancer Biology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
University of Kentucky · USGuangzhou Medical University · CN

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Jennifer F Rogers · 2013 to 2026
$38.3M
EPIGENETIC MECHANISM OF THE SYNERGISTIC TUMORIGENIC EFFECT OF ARSENICAND BENZO[A]PYRENE CO-EXPOSURER01ES028256 · NIEHS · UNIVERSITY OF KENTUCKY · PI WANG, ZHISHAN · 2018 to 2022
$1.8M
MGMT DOWN-REGULATION IN THE CARCINOGENICITY OF HEXAVALENT CHROMIUMR01ES029496 · NIEHS · UNIVERSITY OF KENTUCKY · PI WANG, ZHISHAN · 2019 to 2023
$1.7M
NCI NIH HHS P30 CA177558NIEHS NIH HHS R01 ES028256NIEHS NIH HHS R01 ES029496
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArsenicBenzo(a)pyreneCarcinogenesisCells, CulturedDeubiquitinating EnzymesEpithelial CellsFemaleHumansMiceMice, NudeMyeloid Cell Leukemia Sequence 1 ProteinNeoplastic Stem CellsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal TransductionArsenicBenzo(a)pyreneDeubiquitinating EnzymesMCL1 protein, humanMyeloid Cell Leukemia Sequence 1 ProteinPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesUbiquitin-Specific Peptidase 7USP7 protein, humanarsenicbenzo(a)pyrenecancer stem cell-like propertyMCL-1USP7

Identifiers

PMID32802178
PMCPMC7415806
OpenAlexW3044577069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.