ReviewJournal of pain research2020
Ultrasound-Guided Nerve Hydrodissection for Pain Management: Rationale, Methods, Current Literature, and Theoretical Mechanisms.
Review in Journal of pain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 98 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Ultrasound-Guided Hydrodissection in Patients With Carpal Tunnel Syndrome
Ultrasound Guided Transgluteal Sciatic Nerve Hydrodissection for the Treatment of Sciatica in the Emergency Department
Who cites it
98 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ultrasound-Guided Nerve Hydrodissection for the Management of Carpal Tunnel Syndrome: A Systematic Review and Network Meta-Analysis.Yonsei medical journal · 2025Pooled it
- Comparison of short- and long-axis nerve hydrodissection for carpal tunnel syndrome: A prospective randomized, single-blind trial.International journal of medical sciences · 2021Trial
- Concurrent Long Thoracic and Lateral Cutaneous Intercostal Nerve Entrapment After Chest Tube Thoracostomy Causing Scapular Winging and Chest Wall Pain: Diagnosis With Ultrasound and Treatment With Hydrodissection.Pain practice : the official journal of World Institute of Pain · 2026Article
- Non-Biologic Injections in Sports Medicine.Current reviews in musculoskeletal medicine · 2026Review
- Recent Advances in Ultrasound-Guided Hydrodissection and Dextrose Prolotherapy for Musculoskeletal Pain: A Target-Based State-of-the-Art Narrative Review.Life (Basel, Switzerland) · 2026Review
- Ultrasound-Guided Pharmacopuncture Targeting the Myotendinous Junction for Refractory Common Extensor Tendinopathy: A Case Series.Diagnostics (Basel, Switzerland) · 2026Article
- Cannula Gauge and Tissue Penetration Forces in the Temporal Region: A Biomechanical Basis for Injection Safety.Aesthetic plastic surgery · 2026Article
- Review
- Beyond Corticosteroids: Ultrasound-Guided Regenerative and Hydrodissection Therapies for Adhesive Capsulitis.Life (Basel, Switzerland) · 2026Review
- Ultrasound-Guided Posteromedial Fascial-Periarticular Injection for Mild-to-Moderate Knee Osteoarthritis: Twelve-Month WOMAC Outcomes in a Retrospective Pilot Case Series.Diagnostics (Basel, Switzerland) · 2026Article
- Dynamic Changes in Peripheral Nerve Stiffness After Regional Anesthesia: Implications of Shear Wave Elastography in Adductor Canal Block.Journal of clinical medicine · 2026Review
- Perineuromal hydrodissection for acute postamputation pain? An observational study in a time of war.Regional anesthesia and pain medicine · 2026Observational
- An incidental finding of additional vascular compression of the brachial plexus during ultrasound-guided anterior scalene bupivacaine injection for neurogenic thoracic outlet syndrome: addition of hydrodissection-a case report.Journal of medical case reports · 2026Article
- Review
- Article
- Ultrasound-Guided Lumbar Nerve Root Hydrodissection: Fluoroscopy-Assisted Evaluation of Injectate Distribution and Feasibility.Spine surgery and related research · 2026Article
- Hydraulic fracturing-induced delamination and extravasation extends medial damage beyond the false lumen in aortic dissection.bioRxiv : the preprint server for biology · 2026Article
- Article
- Peripheral Neuropathy: A Phenotype-Driven Review for Diagnosis and Management.Revista de neurologia · 2026Review
- A Conceptual Fascial Memory Reset Hypothesis: Mechanobiological Insights into Stacking Fascia as an Ultrasound-Visible Structural Phenotype and the Potential Role of Fascial Hydrorelease.International journal of molecular sciences · 2026Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nerve hydrodissection (HD), a technique used when treating nerve entrapments, involves the injection of an anesthetic, saline, or 5% dextrose in water to separate the nerve from the surrounding tissue, fascia, or adjacent structures. Animal models suggest the potential for minimal compression to initiate and perpetuate neuropathic pain. Mechanical benefits of HD may relate to release of nervi nervorum or vasa nervorum compression. Pathologic nerves can be identified by examination or ultrasound visualization. The in-plane technique is the predominant and safest method for nerve HD. Five percent dextrose may be favored as the preferred injectate based on preliminary comparative-injectate literature, but additional research is critical. Literature-based hypotheses for a direct ameliorative effect of dextrose HD on neuropathic pain are presented.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.