Evidence map›Paper›PMID 32801805›Full record

ArticleInfection and drug resistance2020

Molecular Investigations of Linezolid Resistance in Enterococci

Pei Li, Yang Yang, Li Ding, Xiaogang Xu, Dongfang Lin

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.3field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Antimicrobial agents and chemotherapy · 2025
    Article
  4. Article
  5. Article
  6. Molecular Characterization of Linezolid-Non-SusceptibleInfection and drug resistance · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Prevalence and genetic diversity ofFrontiers in microbiology · 2024
    Article
  11. A Genomic Snapshot of Antibiotic-ResistantGlobal health, epidemiology and genomics · 2023
    Article
  12. Antibiotics (Basel, Switzerland) · 2022
    Review
  13. Antimicrobial Susceptibility ofAntibiotics (Basel, Switzerland) · 2022
    Article
  14. Emergence ofInfection and drug resistance · 2022
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Pei LiInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Yang YangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Li DingInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Xiaogang XuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Dongfang LinInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Huashan Hospital · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe OptrA protein is a member of ATP-binding cassette (ABC) transporters, a transporter family which can confer resistance to oxazolidinone antibiotics by transferring plasmid. We aim to describe the distribution of

methodsLinezolid-resistance-related genes were tested for

resultsAmong 20

conclusionOptrA exists in linezolid non-resistant enterococci with diverse amino acid substitutions. The variants play different roles in changing the MIC of linezolid.

Indexed as

enterococcilinezolidoptrAresistant

Identifiers

PMID32801805
PMCPMC7414921
OpenAlexW3047174966

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.