Evidence map›Paper›PMID 32801720›Full record

ArticleNeuropsychiatric disease and treatment2020

Protective Role of Astrocyte-Derived Exosomal

Xiancong Bu, Dong Li, Feng Wang, Qimeng Sun, Zixian Zhang

RetractedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropsychiatric disease and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. MicroRNA Profiles in Critically Ill Patients.Current medicinal chemistry · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiancong BuDepartment of Neurology, Zaozhuang Municipal Hospital, Zaozhuang, Shandong 277100, People's Republic of China.
Dong LiDepartment of Neurology, Zaozhuang Hospital of Zaozhuang Mining Group, Zaozhuang, Shandong 277100, People's Republic of China.
Feng WangDepartment of Neurology, Zaozhuang Municipal Hospital, Zaozhuang, Shandong 277100, People's Republic of China.
Qimeng SunDepartment of Neurology, Zaozhuang Municipal Hospital, Zaozhuang, Shandong 277100, People's Republic of China.
Zixian ZhangDepartment of Neurology, Zaozhuang Municipal Hospital, Zaozhuang, Shandong 277100, People's Republic of China.
Zaozhuang Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence has shown that microRNAs (miRNAs) are implicated in ischemic diseases. Therefore, the aim of the present study was to identify the functions of astrocyte (ATC)-derived exosomal

methodsA rat model of cerebral I/R injury was initially established, followed by injection of ATC-derived exosomes. Next, the protective function of ATC-derived exosomes in rats with cerebral I/R injury was evaluated, and then the effect of

resultsIt was found that I/R was damaging to the brain nerves of rats, while ATC-derived exosomal

conclusionThe present study demonstrated that ATC-derived exosomal

Indexed as

AMPK/mTOR signaling pathwayastrocytecathepsin Bcerebral ischemic-reperfusion injuryexosomemicroRNA-361

Identifiers

PMID32801720
PMCPMC7410492
OpenAlexW3046223651

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.