Evidence map›Paper›PMID 32801715›Full record

ArticleNeuropsychiatric disease and treatment2020

Gastrointestinal Problems in Chinese Children with Autism Spectrum Disorder.

Kelly Y C Lai, Patrick W L Leung, Se Fong Hung, Caroline K S Shea, Flora Mo, Kiti K I Che, Chun-Yu Tse, Fanny L F Lau, Suk Ling Ma, Justin C Y Wu and 2 more

Abstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. mSystems · 2024
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kelly Y C LaiDepartment of Psychiatry, Chinese University of Hong Kong, Shatin, Hong Kong.ORCID 0000-0001-8623-6089
Patrick W L LeungDepartment of Psychology, Chinese University of Hong Kong, Shatin, Hong Kong.ORCID 0000-0002-0415-0124
Se Fong HungDepartment of Psychiatry, Chinese University of Hong Kong, Shatin, Hong Kong.
Caroline K S SheaDepartment of Psychiatry, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong.
Flora MoDepartment of Psychiatry, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong.
Kiti K I CheDepartment of Psychiatry, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong.
Chun-Yu TseDepartment of Psychology, Chinese University of Hong Kong, Shatin, Hong Kong.ORCID 0000-0002-6120-2971
Fanny L F LauDepartment of Psychiatry, Chinese University of Hong Kong, Shatin, Hong Kong.
Suk Ling MaDepartment of Psychiatry, Chinese University of Hong Kong, Shatin, Hong Kong.ORCID 0000-0001-6175-5691
Justin C Y WuDepartment of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong.
Suzanne SoDepartment of Psychology, Chinese University of Hong Kong, Shatin, Hong Kong.
Mark R DaddsSchool of Psychology, University of Sydney, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGastrointestinal symptoms in individuals with autism spectrum disorder may constitute a subgroup with complex gut-brain interactions underlying the pathogenesis. This study examined the prevalence of gastrointestinal symptoms in a sample of Chinese children with autism spectrum disorder, as well as the factors related to them. PARTICIPANTS AND

methodsThe participants included a clinic sample of 107 children with autism spectrum disorder and 249 gender- and age-matched typically developing community children.

resultsResults found children with autism spectrum disorder to be twice as likely to suffer from gastrointestinal symptoms, reporting increased rates of constipation, abdominal migraine and aerophagia. Autism spectrum disorder diagnosis remained a significant predictor of gastrointestinal symptoms after taking into account the potential confounders that included comorbid psychopathologies, diets, and parental anxiety and depression.

conclusionOur results suggest that autism spectrum disorder with gastrointestinal symptoms may constitute a subgroup within the autism spectrum disorder population that warrants further investigation.

Indexed as

autism spectrum disorderchildrenChinesegastrointestinal symptomssubgroup

Identifiers

PMID32801715
PMCPMC7386814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.