Evidence map›Paper›PMID 32801701›Full record

ArticleInternational journal of nanomedicine2020

Specific Anti-biofilm Activity of Carbon Quantum Dots by Destroying

Gaofeng Liang, Hao Shi, Yijun Qi, Jinghua Li, Aihua Jing, Qiwei Liu, Wenpo Feng, Guangda Li, Shegan Gao

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
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  9. Biogenic synthesis of silver nanoparticles usingBiotechnology notes (Amsterdam, Netherlands) · 2025
    Article
  10. On the Use of Nanoparticles in Dental Implants.Materials (Basel, Switzerland) · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
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  16. Article
  17. Recent progress in carbon dots for anti-pathogen applications in oral cavity.Frontiers in cellular and infection microbiology · 2023
    Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gaofeng LiangMedical College, Henan University of Science and Technology, Luoyang 471023, People's Republic of China.ORCID 0000-0003-0097-0296
Hao ShiSchool of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471023, People's Republic of China.
Yijun QiMedical College, Henan University of Science and Technology, Luoyang 471023, People's Republic of China.
Jinghua LiSchool of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471023, People's Republic of China.
Aihua JingSchool of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471023, People's Republic of China.
Qiwei LiuHenan Key Laboratory of Cancer Epigenetics, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471023, People's Republic of China.
Wenpo FengMedical College, Henan University of Science and Technology, Luoyang 471023, People's Republic of China.
Guangda LiSchool of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471023, People's Republic of China.
Shegan GaoMedical College, Henan University of Science and Technology, Luoyang 471023, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBiofilms protect bacteria from antibiotics and this can produce drug-resistant strains, especially the main pathogen of periodontitis,

methodsTinidazole carbon quantum dots (TCDs) and metronidazole carbon quantum dots (MCDs) were prepared by a hydrothermal method with the clinical antibacterial drugs tinidazole and metronidazole, respectively. Then, TCDs and MCDs were characterized by transmission electron microscopy, UV-visible spectroscopy, infrared spectroscopy and energy-dispersive spectrometry. The antibacterial effects were also investigated under different conditions.

resultsThe TCDs and MCDs had uniform sizes. The results of UV-visible and energy-dispersive spectrometry confirmed their important carbon polymerization structures and the activity of the nitro group, which had an evident inhibitory effect on

conclusionThe findings demonstrate a promising new method for improving the efficiency of periodontitis treatment by penetrating the

Indexed as

AnimalsAnti-Bacterial AgentsBacterial AdhesionBiofilmsCarbonEscherichia coliGene Expression Regulation, BacterialHumansMetronidazoleMicrobial Sensitivity TestsMicroscopy, Electron, TransmissionPeriodontitisPorphyromonas gingivalisQuantum DotsRabbitsSpectrophotometry, UltravioletAnti-Bacterial AgentsCarbonMetronidazoleTinidazoleVirulence Factorsbiofilmscarbon dotspenetrationP. gingivalisTinidazole

Identifiers

PMID32801701
PMCPMC7406331

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.