Evidence map›Paper›PMID 32801688›Full record

ArticleInternational journal of nanomedicine2020

Comprehensive Analysis of SiNPs on the Genome-Wide Transcriptional Changes in

Shuang Liang, Junchao Duan, Hejing Hu, Jingyi Zhang, Shan Gao, Haiming Jing, Guojun Li, Zhiwei Sun

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. HarnessingMicroorganisms · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shuang Liang *Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, People's Republic of China.
Junchao Duan *Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, People's Republic of China.
Hejing HuDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, People's Republic of China.
Jingyi ZhangDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, People's Republic of China.
Shan GaoBeijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, People's Republic of China.
Haiming JingBeijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, People's Republic of China.ORCID 0000-0001-9107-036X
Guojun LiBeijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, People's Republic of China.
Zhiwei SunDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, People's Republic of China.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLarge-scale production and application of amorphous silica nanoparticles (SiNPs) have enhanced the risk of human exposure to SiNPs. However, the toxic effects and the underlying biological mechanisms of SiNPs on PURPOSE: This study was to investigate the genome-wide transcriptional alteration of SiNPs on METHODS AND

resultsIn this study, a total number of 3105 differentially expressed genes were identified in

conclusionOur study showed that SiNPs induced the change of the whole transcriptome in

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsGene Expression RegulationGene Regulatory NetworksGenome, HelminthHumansLongevityMicroRNAsMutagenicity TestsNanoparticlesReproductionSignal TransductionSilicon DioxideTranscriptomeUnfolded Protein ResponseCaenorhabditis elegans ProteinsMicroRNAsSilicon DioxideCaenorhabditis elegansdevelopmentgenome microarrayslongevitySiNPs

Identifiers

PMID32801688
PMCPMC7399461
OpenAlexW3044270876

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.