Evidence map›Paper›PMID 32801638›Full record

ArticleDrug design, development and therapy2020

Potential Allylpyrocatechol Derivatives as Antibacterial Agent Against Oral Pathogen of

Dikdik Kurnia, Geofanny Sarah Hutabarat, Devi Windaryanti, Tati Herlina, Yetty Herdiyati, Mieke Hemiawati Satari

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Bioactive Constituents ofDrug design, development and therapy · 2026
    Review
  3. Review
  4. Antifungal Constituents ofMolecules (Basel, Switzerland) · 2023
    Article
  5. Review
  6. Review
  7. The Potential of 24-Propylcholestrol as Antibacterial Oral Bacteria ofAdvances and applications in bioinformatics and chemistry : AABC · 2022
    Article
  8. Predominance of non-Saudi journal of biological sciences · 2021
    Article
  9. Article
  10. Molecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dikdik KurniaDepartment of Chemistry, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Sumedang, Indonesia.ORCID 0000-0001-9789-9785
Geofanny Sarah HutabaratDepartment of Chemistry, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Sumedang, Indonesia.ORCID 0000-0003-4862-4202
Devi WindaryantiDepartment of Chemistry, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Sumedang, Indonesia.
Tati HerlinaDepartment of Chemistry, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Sumedang, Indonesia.
Yetty HerdiyatiDepartment of Pediatric Dentistry, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia.
Mieke Hemiawati SatariDepartment of Oral Biology, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia.ORCID 0000-0002-6021-9480
Padjadjaran University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPURPOSE: The study aims to identify antibacterial constituents of MATERIALS AND

methodsThe antibacterial agent was purified by bioactivity-guided isolation with combination chromatography methods and the chemical structure was determined by spectroscopic methods. The in vitro antibacterial activity was evaluated by disc diffusion and dilution methods while the in silico study of a compound binds on the MurA was determined using PyRx program.

resultsThe antibacterial compound identified as allylpyrocatechol showed inhibitory activity against

conclusionTwo allylpyrocatechol derivatives were predicted to have a good potency as a novel natural antibacterial agent against

Indexed as

Alkyl and Aryl TransferasesAnti-Bacterial AgentsCatecholsDose-Response Relationship, DrugEnzyme InhibitorsMicrobial Sensitivity TestsMolecular StructurePiper betlePlant ExtractsPlant LeavesStreptococcus sanguisStructure-Activity RelationshipAlkyl and Aryl TransferasesallylpyrocatecholAnti-Bacterial AgentsCatecholsEnzyme InhibitorsPlant ExtractsUDP-N-acetylglucosamine 1-carboxyvinyltransferaseallylpyrocatecholMurA enzymePiper betle L.Streptococcus sanguinis

Identifiers

PMID32801638
PMCPMC7396738
OpenAlexW3043989942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.