ReviewClinical ophthalmology (Auckland, N.Z.)2020
Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole.
Review in Clinical ophthalmology (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Autologous platelet concentrate for the treatment of macular hole: a systematic review and meta-analysis.Einstein (Sao Paulo, Brazil) · 2024Pooled it
- Chromovitrectomy: current evidence, emerging technologies, and practical applications in vitreoretinal surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Review
- Anatomical and Functional Outcomes of Platelet-Rich Plasma-Assisted Surgery for Full-Thickness Macular Holes: A Retrospective Real-World Cohort Study.Journal of clinical medicine · 2026Article
- Anatomical and functional outcomes and prognostic factors after idiopathic full-thickness macular hole surgery: a single-center retrospective cohort study.BMC ophthalmology · 2026Article
- Assessment of internal limiting membrane flap and autologous whole blood techniques in complicated macular hole surgery.BMC ophthalmology · 2026Article
- Positive Rotational Internal Limiting Membrane Covering Technique for Large Idiopathic Macular Holes.Journal of ophthalmology · 2026Article
- Predicting anatomical success and retinal restoration following macular hole surgery using optical coherence tomography parameters.BMC ophthalmology · 2025Article
- Ceruloplasmin and Ferritin Changes in Ocular Fluids from Patients with Vitreoretinal Diseases: Relation with Neuroinflammation and Drusen Formation.International journal of molecular sciences · 2025Article
- Development of a prognostic surgical index using optical coherence tomography for large macular holes: a retrospective multicenter study.BMC ophthalmology · 2025Article
- Accidental diode laser-induced full-thickness macular hole: a case report.BMC ophthalmology · 2025Article
- Efficacy of a simple intravitreal perfluoropropane injection in treating unclosed idiopathic macular holes following vitrectomy.BMC ophthalmology · 2025Observational
- Article
- Morphological alterations of macular region in fellow eyes of patients with idiopathic full-thickness macular holes detected by optical coherence tomography.International journal of ophthalmology · 2025Article
- Long-Term Results of Pars Plana Vitrectomy with Internal Limiting Membrane Peeling for Vitreomacular Traction Syndrome: A Prospective Investigation in Central Asian Population.Healthcare (Basel, Switzerland) · 2024Article
- Comparative analysis of pre-operative findings and post-operative outcomes in primary and secondary macular holes at a tertiary eye hospital in South India.International journal of retina and vitreous · 2024Article
- Platelet concentrates in macular hole surgery. A journey through the labyrinth of terminology, preparation, and application: a comprehensive review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Review
- Analysis of the progression rate of idiopathic macular holes and the optimal cut-off for baseline minimum linear diameter and base diameter.Japanese journal of ophthalmology · 2024Article
- Prediction of foveal microstructure and visual outcomes following surgery for idiopathic macular hole: An assessment using spectral-domain optical coherence tomography.Indian journal of ophthalmology · 2024Article
- Novel Artificial Intelligence-Based Assessment of Imaging Biomarkers in Full-Thickness Macular Holes: Preliminary Data from a Pivotal Trial.Journal of clinical medicine · 2024Article
- Partial Detachment of an ILM Inverted Flap After a Successful Closure of a Full-Thickness Traumatic Macular Hole.International medical case reports journal · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo summarize current surgical techniques for treating primary macular holes (MHs).
methodsWe reviewed publications detailing surgical approaches to primary MHs, briefly described their protocols, and outlined their results.
resultsCurrently, the technique for primary MH repair is pars plana vitrectomy, removing the posterior cortical vitreous, stripping the epiretinal membranes, and ending with intraocular gas tamponade. The evident benefit of peeling off the internal limiting membrane (ILM) was clearly shown for MHs at stages 2 to 4 by achieving an anatomical closure rate of >90%, even in large MH up to 650 µm. Newer MH surgical techniques include modification of ILM flap techniques, placing an autologous scaffolding of tissue within the hole, and cell therapy has shown to increase the closure rate of large and chronic macular holes, resulting in modest functional improvement in complicated MHs.
conclusionSince the turn of the century, the success rate of modern macular surgery has increased, even for large and chronic MHs. There seems to be no limit to novel concepts in MH surgery, which range from anatomical closure to those proposing natural restoration of visual function via stem cell therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.