Evidence map›Paper›PMID 32801618›Full record

ReviewClinical ophthalmology (Auckland, N.Z.)2020

Clinical-Decision Criteria to Identify Recurrent Diabetic Macular Edema Patients Suitable for Fluocinolone Acetonide Implant Therapy (ILUVIEN

Alfredo Adán, Francisco Cabrera, Marta S Figueroa, Enrique Cervera, Francisco J Ascaso, Patricia Udaondo, Maximino Abraldes, Miguel Ángel Reyes, Marta Pazos, Bernardete Pessoa and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Clinical ophthalmology (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 2 countries.

Alfredo AdánHospital Clínic de Barcelona, Barcelona, Spain.ORCID 0000-0001-8923-2200
Francisco CabreraComplejo Hospitalario Universitario Insular Materno-Lnfantil de Gran Canaria, Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-5074-5102
Marta S FigueroaHospital Universitario Ramón y Cajal, Madrid, Spain.
Enrique CerveraHospital General Universitario de Valencia, Valencia, Spain.
Francisco J AscasoHospital Clínico Universitario Lozano Blesa de Zaragoza, Aragon Health Research Institute (IIS Aragon), Zaragoza, Spain.
Patricia UdaondoHospital Universitario y Politécnico la Fe de Valencia, Valencia, Spain.ORCID 0000-0002-5241-0066
Maximino AbraldesComplexo Hospitalario Universitario de Santiago de Compostela, Universidad de Santiago de Compostela, Instituto Oftalmológico Gómez-Ulla, Santiago de Compostela, Spain.ORCID 0000-0001-8100-5433
Miguel Ángel ReyesHospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Spain.ORCID 0000-0001-7128-8134
Marta PazosHospital Clínic de Barcelona, Barcelona, Spain.
Bernardete PessoaCentro Hospitalar e Universitário do Porto, Hospital Geral de Santo António, Porto, Portugal.ORCID 0000-0002-5673-1561
Félix ArmadáHospital Universitario La Paz, Madrid, Spain.ORCID 0000-0002-3695-3343
Hospital Clínic de Barcelona · ESHospital Clínico Universitario Lozano Blesa · ESHospital de Santo António · PTHospital General Universitario De Valencia · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario de Gran Canaria Doctor Negrín · ESHospital Universitario Insular de Gran Canaria · ESHospital Universitario La Paz · ESHospital Universitario Ramón y Cajal · ESUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current management of diabetic macular edema (DME) predominantly involves treatment with short-acting intravitreal injections of anti-vascular endothelial growth factors (anti-VEGFs) and/or corticosteroids; however, short-acting therapies (lasting between 1 and 6 months) require frequent injections to maintain efficacy, meaning a considerable treatment burden for diabetic patients with multiple comorbidities. Continuous injections needed in some cases are an economic burden for patients/healthcare system, so real-life clinical practice tends to adopt a reactive approach, ie, watch and wait for worsening symptoms, which consequently increases the risk of undertreatment and edema recurrence. On March 7th 2019, a group of experts in retinal medicine and surgery held a roundtable meeting in Madrid, Spain to discuss how to (1) optimize clinical outcomes through earlier use of fluocinolone acetonide (FAc) implant (ILUVIEN

Indexed as

diabetic macular edemaDMEfluocinolone acetonide implant therapyILUVIEN

Identifiers

PMID32801618
PMCPMC7398681
OpenAlexW3044910002

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.