Evidence map›Paper›PMID 32801509›Full record

ArticleJournal of parasitic diseases : official organ of the Indian Society for Parasitology2020

Apigenin effect against Leishmania tropica amastigotes in vitro.

Nagham Naddaf, Shaden Haddad

Open access · greenAbstract read
In one paragraph

Article in Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nagham NaddafDepartment of Biochemistry and Microbiology, Faculty of Pharmacy, Damascus University, Damascus, Syria.ORCID 0000-0002-4297-2815
Shaden HaddadDepartment of Biochemistry and Microbiology, Faculty of Pharmacy, Damascus University, Damascus, Syria.
Damascus University · SY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous Leishmaniasis is a current public health problem in Syria. It causes different skin lesions that vary in their severity from spontaneously heal lesions to permanent deformity ones. However, the used treatments have many disadvantages as their high toxicity and many side effects. Flavonoids including Apigenin reported to have many anti parasitic properties. As well as their preference as potential therapeutic alternatives in the treatment of Leishmaniasis due to its low side effects and toxicity. This study aims to evaluate the efficacy of Apigenin against L.tropica amastigotes in vitro using Leishmania-Macrophage Interaction Assay. Our study demonstrated the possibility of efficacy of Apigenin against L.tropica amastigotes since Apigenin reduced the infection index at IC

Indexed as

AmastigotesApigeninCutaneous LeishmaniasisFlavonoidsInfection indexL. tropicaMacrophage

Identifiers

PMID32801509
PMCPMC7410876
OpenAlexW3026781778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.