ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2020
Colorimetric Determination of Urinary Creatinine in Proteinuria Patients by Chromaticity Analysis of Gold Nanoparticle Colloidal Solutions.
Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Ratio-fluorescent and naked-eye visualized dual-channel sensing strategy for CuAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024Article
- Colorimetric Detection Based on Localized Surface Plasmon Resonance for Determination of Chemicals in Urine.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021Article
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4 authors.
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Abstract
Several scientific works have reported the use of colloidal gold nanoparticle (AuNP) solutions as a colorimetric probe for creatinine detection. Nonetheless, urinary protein is one of the primary chemical components that can interfere with creatinine detection. In this work, we developed a colorimetric probe using AuNP colloidal solution to detect creatinine in the urine of proteinuria patients. A microchamber array was prepared to minimize the sample volume and was used to simultaneously perform spectral recording and image acquisition of several samples. The analyzed volume for each sample was 15 μL. A camera coupled with liquid crystal tunable filters was used to record hyperspectral images, and the signals were then converted to localized surface plasmon resonance (LSPR) spectra. Color changes in the AuNP colloidal solution in the presence of varying concentrations of creatinine and human serum albumin (HSA) indicated different features and could be detected by a hyperspectral imaging technique. The relevant concentration ranges of creatinine and HSA were 5 - 200 and 50 - 250 mg dL
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