Evidence map›Paper›PMID 32801228›Full record

ArticleEndoscopic ultrasound

Predicting pediatric esophageal wall thickness: An EUS study.

Simon S Rabinowitz, Evan Grossman, Lisa Feng, Nonyelum Ebigbo, Bo Lin, Raavi Gupta, Rachel Sklar, Steven M Schwarz, Jeremy Weedon, Frank Gress

Abstract read
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Article in Endoscopic ultrasound. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Simon S RabinowitzDivision of Pediatric Gastroenterology, Children's Hospital at Brooklyn, New York, USA.
Evan GrossmanDivision of Gastroenterology & Hepatology, Department of Medicine, SUNY Downstate College of Medicine, Brooklyn, New York, USA.
Lisa FengDivision of Pediatric Gastroenterology, Children's Hospital at Brooklyn, New York, USA.
Nonyelum EbigboDivision of Pediatric Gastroenterology, Children's Hospital at Brooklyn, New York, USA.
Bo LinDepartment of Pathology, SUNY Downstate College of Medicine, Brooklyn, New York, USA.
Raavi GuptaDepartment of Pathology, SUNY Downstate College of Medicine, Brooklyn, New York, USA.
Rachel SklarDivision of Pediatric Gastroenterology, Children's Hospital at Brooklyn, New York, USA.
Steven M SchwarzDivision of Pediatric Gastroenterology, Children's Hospital at Brooklyn, New York, USA.
Jeremy WeedonStatistical Design & Analysis, Research Division, SUNY Downstate College of Medicine, Brooklyn, New York, USA.
Frank GressDivision of Gastroenterology & Hepatology, Department of Medicine, SUNY Downstate College of Medicine, Brooklyn, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveEUS has been shown in two small series to be capable of documenting increases in the total esophageal wall thickness (TWT) in children and adults with eosinophilic esophagitis (EoE). To apply EUS-derived TWT in clinical situations or in scientific investigations in pediatric EoE, measurements of esophageal TWT in children of differing ages and heights are required. MATERIALS AND

methodsThirty patients (18M: 12F, 7 months to 20 years and 10 months) with a history of esophageal symptoms, but no endoscopic or histologic criteria of EoE were studied using a through the scope 20 MHZ Olympus Ultrasound miniprobe UM-3R (Olympus America, Center Valley Pa 18034) through a GIF Q180 or 160 (Olympus) standard pediatric upper endoscope. The mucosa, the mucosa plus submucosa, and the TWT were measured in the mid- and distal esophagus immediately before taking diagnostic biopsies.

resultsMeasurements from both sites showed a statistically significant increase in TWT as a function of age (P < 0.001) and height (P < 0.001), as did the individual layers. The width of the mucosa and the submucosa were equivalent and together, they contributed more than half of the entire TWT. There were no significant differences between the means of the mid- and distal esophageal measurements. A multiple regression equation that can predict TWT based on age, with 95% confidence limits, is presented.

conclusionsEUS has demonstrated that esophageal TWT in a cohort of control children correlates with height and with age and has provided insights into the organization of the esophageal wall. Esophageal TWT values obtained by EUS can now be interpreted to recognize esophageal wall thickening throughout childhood.

Indexed as

esophagusEUSpediatrics

Identifiers

PMID32801228
PMCPMC7529003

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.