ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2021
Associations Between Reproductive and Hormone-Related Factors and Risk of Nonalcoholic Fatty Liver Disease in a Multiethnic Population.
Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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27 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Systematic review with meta-analysis: Non-alcoholic fatty liver disease and the association with pregnancy outcomes.Clinical and molecular hepatology · 2022Pooled it
- Impact of Menopause and Menopausal Hormone Therapy on Liver-Kidney-Metabolic Health.Advances in therapy · 2026Review
- Incidence of Metabolic Dysfunction-Associated Steatotic Liver Disease After Developing Depression: A Population-Based Cohort Study.Journal of Korean medical science · 2026Article
- From Childhood to Old Age: Current Knowledge and Practical Approaches to Metabolic Dysfunction-Associated Steatotic Liver Disease.Journal of clinical medicine · 2026Review
- Earlier Menopause and Risk of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Global Cohort Study.Diabetes/metabolism research and reviews · 2026Article
- Article
- The Impact of Estrogen Deficiency on Liver Metabolism: Implications for Hormone Replacement Therapy.Endocrine reviews · 2025Review
- Sex Hormones and Metabolic Dysfunction-Associated Steatotic Liver Disease.International journal of molecular sciences · 2025Review
- The impact of parity on the risk of nonalcoholic fatty liver disease defined by hepatic steatosis index: A nationwide cohort study.Scientific reports · 2025Article
- Laparoscopically confirmed endometriosis and the risk of incident NAFLD: a prospective cohort study.Reproductive biology and endocrinology : RB&E · 2025Article
- Hypogonadism and nonalcoholic fatty liver disease.Endocrine · 2024Review
- An Unusual Cause of Massive Per Vaginal Bleeding.ACG case reports journal · 2024Article
- Helicobacter pylori infection is associated with liver fibrosis in patients with obesity undergoing bariatric surgery.JGH open : an open access journal of gastroenterology and hepatology · 2024Article
- Norethindrone-Associated Transaminitis in Endometriosis Patients: A Case Series and Literature Review.Cureus · 2024Article
- [Analysis of non-alcoholic fatty liver disease differences from metabolic dysfunction-associated fatty liver disease based on clinical features].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024Article
- Association of hysterectomy with nonalcoholic fatty liver disease among US women.Lipids in health and disease · 2024Article
- Health condition and socioeconomic status mediate the causal effect of reproductive traits on nonalcoholic fatty liver disease: evidence from Mendelian randomization study.Frontiers in endocrinology · 2024Article
- 17β-Estradiol (EAntioxidants (Basel, Switzerland) · 2023Article
- Association of age at first birth and risk of non-alcoholic fatty liver disease in women: evidence from the NHANES.Hepatology international · 2023Article
- Life-course fertility and multimorbidity among middle-aged and elderly women in China: Evidence from China health and retirement longitudinal study.Frontiers in public health · 2023Article
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
BACKGROUND &
aimsDespite apparent differences between men and women in the prevalence and incidence of nonalcoholic fatty liver disease (NAFLD), there are limited epidemiologic data regarding the associations of reproductive and hormone-related factors with NAFLD. We examined the associations of these factors and exogenous hormone use with NAFLD risk in African American, Japanese American, Latino, Native Hawaiian, and white women.
methodsWe conducted a nested case-control study (1861 cases and 17,664 controls) in the Multiethnic Cohort Study. NAFLD cases were identified using Medicare claims data; controls were selected among participants without liver disease and individually matched to cases by birth year, ethnicity, and length of Medicare enrollment. Reproductive and hormone-related factors and covariates were obtained from the baseline questionnaire. Multivariable logistic regression was used to calculate odds ratios (ORs) and 95% CIs.
resultsLater age at menarche was associated inversely with NAFLD (P
conclusionsFindings from a large multiethnic study support the concept that menstrual and reproductive factors, as well as the use of exogenous hormones, are associated with the risk of NAFLD.
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