Evidence map›Paper›PMID 32800455›Full record

ArticleTrends in immunology2020

Location, Location, Location: Transcriptional Control of Astrocyte Heterogeneity.

Marci F Rosenberg, Anna V Molofsky

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Marci F RosenbergDepartment of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, 94158, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, 94158, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, 94158, USA.
Anna V MolofskyDepartment of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, 94158, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, 94158, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, 94158, USA. Electronic address: anna.molofsky@ucsf.edu.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007618 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANDERSON, MARK S · 1985 to 2020
$29.6M
Coordinate regulation of neural circuit remodeling by glia: a prospective molecular approachDP2MH116507 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MOLOFSKY, ANNA V · 2017 to 2017
$2.4M
Astrocyte-microglial communication in developmental synapse formationR01MH119349 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MOLOFSKY, ANNA V · 2019 to 2023
$2.0M
Noradrenergic regulation of grey-matter astrocyte maturationF30MH124367 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ROSENBERG, MARCI · 2020 to 2023
$181k
NIGMS NIH HHS T32 GM007618NIMH NIH HHS DP2 MH116507NIMH NIH HHS F30 MH124367NIMH NIH HHS R01 MH119349
6 · The paper itself

Abstract

Huang et al. have found that deletion of astrocyte lineage-specifying transcription factor NFIA from mature astrocytes alters astrocyte morphology, molecular identity, and synaptic-support capacity in a region-specific manner. We discuss the implications of these findings in light of emerging roles for astrocytes in immune cell crosstalk.

Indexed as

AstrocytesHumans

Identifiers

PMID32800455
PMCPMC8214865

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.