ArticleBehavior therapy2020
Reward Responsiveness and Ruminative Styles Interact to Predict Inflammation and Mood Symptomatology.
Article in Behavior therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- A systematic review of associations between emotion regulation characteristics and inflammation.Neuroscience and biobehavioral reviews · 2023Pooled it
- Psychoneuroimmunological Evidence for Biological Embedding During Early Adolescence.Developmental psychobiology · 2025Article
- Toward diversification of acute stressors and precision stress research: A stage 2 Registered Report validating a reward-salient stress task in emerging adults.Journal of psychopathology and clinical science · 2025Article
- Splitting the reward: Differences in inflammatory marker associations with neural connectivity between reward anticipation and reward outcome in adolescents at high risk for depression.Journal of affective disorders · 2023Article
- Mood Symptom Dimensions and Developmental Differences in Neurocognition in Adolescence.Clinical psychological science : a journal of the Association for Psychological Science · 2023Article
- Protocol for project MIME: Motivation, inflammation, and Mood in Emerging Adults.Brain, behavior, & immunity - health · 2022Article
- Neuroinflammation and neuroprogression in depression: Effects of alternative drug treatments.Brain, behavior, & immunity - health · 2022Review
- Residence in High-Crime Neighborhoods Moderates the Association Between Interleukin 6 and Social and Nonsocial Reward Brain Responses.Biological psychiatry global open science · 2022Article
- Understanding associations between rumination and inflammation: A scoping review.Neuroscience and biobehavioral reviews · 2022Article
- Depressive symptoms and other negative psychological states relate to ex vivo inflammatory responses differently for men and women: Cross-sectional and longitudinal evidence.Physiology & behavior · 2022Article
- A physiometric investigation of inflammatory composites: Comparison of "a priori" aggregates, empirically-identified factors, and individual proteins.Brain, behavior, & immunity - health · 2021Article
- Inflammation Predicts Sexual Arousability in Healthy Women.Comprehensive psychoneuroendocrinology · 2021Article
- Building a replicable and clinically-impactful immunopsychiatry: Methods, phenotyping, and theory integration.Brain, behavior, & immunity - health · 2021Article
- Goal-striving tendencies moderate the relationship between reward-related brain function and peripheral inflammation.Brain, behavior, and immunity · 2021Article
- Back to Basics: The Importance of Measurement Properties in Biological Psychiatry.Neuroscience and biobehavioral reviews · 2021Review
- Behavioral Inhibition/Activation Systems and Depression Among Females With Substance Use Disorder: The Mediating Role of Intolerance of Uncertainty and Anhedonia.Frontiers in psychiatry · 2021Article
- How handling extreme C-reactive protein (CRP) values and regularization influences CRP and depression criteria associations in network analyses.Brain, behavior, and immunity · 2021Article
- Reward Sensitivity, Cognitive Response Style, and Inflammatory Response to an Acute Stressor in Adolescents.Journal of youth and adolescence · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Abnormal reward responsiveness and rumination each are associated with elevated inflammation and mood symptoms. Ruminating on positive and negative affect, or dampening positive affect, may amplify, or buffer, the associations of reward hyper/hyposensitivity with inflammation and mood symptoms. Young adults (N = 109) with high or moderate reward sensitivity completed reward responsiveness and ruminative style measures at the initial visit of a longitudinal study of mood symptoms, a blood draw to assess inflammatory biomarkers, and mood symptom measures at the study visits before and after the day of the blood draw. The interaction between high reward responsiveness and rumination on positive affect was associated with higher levels of an inflammatory composite measure and hypomanic symptoms. The interaction between lower reward responsiveness and high dampening of positive affect was associated with higher levels of the inflammatory composite measure and depressive symptoms. Lower reward responsiveness also interacted with low rumination on positive affect to predict increases in depressive symptoms and higher levels of the inflammatory composite. Thus, levels of reward responsiveness and ruminative response styles may synergistically influence the development of inflammatory phenotypes and both hypomanic and depressive mood symptoms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.