Evidence map›Paper›PMID 32800084›Full record

ArticleJournal of studies on alcohol and drugs2020

Cognitive Functioning Related to Binge Alcohol and Cannabis Co-Use in Abstinent Adolescents and Young Adults.

Natasha E Wade, Kara S Bagot, Susan F Tapert, Staci A Gruber, Francesca M Filbey, Krista M Lisdahl

Open access · greenAbstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Longitudinal neurocognitive trajectories in a large cohort of youth who use cannabis: combining self-report and toxicology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Natasha E WadeDepartment of Psychiatry, University of California San Diego, La Jolla, California.
Kara S BagotDepartment of Psychiatry, University of California San Diego, La Jolla, California.
Susan F TapertDepartment of Psychiatry, University of California San Diego, La Jolla, California.
Staci A GruberImaging Center, McLean Hospital, Department of Psychiatry, Harvard Medical School, Cambridge, Massachusetts.
Francesca M FilbeyBert Moore Chair in BrainHealth, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, Texas.
Krista M LisdahlDepartment of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin.
University of California, San Diego · USMcLean Hospital · USThe University of Texas at Dallas · USUniversity of Wisconsin–Milwaukee · US

Funding

AACAP Physician Scientist Program in Substance UseK12DA000357 · NIDA · AMERICAN ACADEMY-CHILD/ADOLESCENT PSYCH · PI Kevin M. Gray · 1998 to 2026
$29.1M
ABCD-USA Consortium: UWM SIte U01DA041025 · NIDA · UNIVERSITY OF WISCONSIN MILWAUKEE · PI Christine L Larson, Krista Maurine Lisdahl · 2017 to 2026
$11.2M
Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
TRANSLATIONAL CTR ON THE CLINICAL NEUROBIOL OF CANNABIS ADDICTIONP20DA024194 · NIDA · SCRIPPS RESEARCH INSTITUTE, THE · PI MASON, BARBARA J · 2007 to 2010
$3.8M
IDEAA: UWM SiteR01DA030354 · NIDA · UNIVERSITY OF WISCONSIN MILWAUKEE · PI LISDAHL, KRISTA MAURINE · 2011 to 2017
$2.7M
The Role of Motivation and Control in Cannabis Use Disorders: A Cross-Cultural Longitudinal Neuroimaging StudyR01DA042490 · NIDA · UNIVERSITY OF TEXAS DALLAS · PI COUSIJN, JANNA, FILBEY, FRANCESCA · 2017 to 2021
$2.6M
Genetic and Environmental Modulators of the Brain's Response to Marijuana CuesR01DA030344 · NIDA · UNIVERSITY OF TEXAS DALLAS · PI FILBEY, FRANCESCA · 2012 to 2016
$2.4M
Marijuana: Neurobiologic Correlates of Age of OnsetR01DA032646 · NIDA · MCLEAN HOSPITAL · PI GRUBER, STACI A · 2012 to 2016
$2.0M
fMRI and Cognition in Adolescent Cannabis UsersR01DA021182 · NIDA · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI TAPERT, SUSAN F · 2006 to 2010
$1.8M
fMRI and Treatment Response with Binge Drinking AdolescentsR01AA023658 · NIAAA · UNIVERSITY OF RHODE ISLAND · PI FELDSTEIN EWING, SARAH W. · 2015 to 2019
$1.7M
Frontal Neural Mechanisms and Risk for Substance AbuseR03DA016695 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI GRUBER, STACI A · 2003 to 2003
$206k
NIAAA NIH HHS R01 AA023658NIAAA NIH HHS T32 AA013525NIDA NIH HHS K12 DA000357NIDA NIH HHS P20 DA024194NIDA NIH HHS R01 DA021182NIDA NIH HHS R01 DA030344NIDA NIH HHS R01 DA030354NIDA NIH HHS R01 DA032646NIDA NIH HHS R01 DA042490NIDA NIH HHS R03 DA016695NIDA NIH HHS U01 DA041025
6 · The paper itself

Abstract

objectiveDespite preliminary evidence of unique acute cognitive and psychopharmacological changes attributable to combined alcohol and cannabis use, few studies have investigated more chronic effects of same-day co-use, particularly during neurodevelopmentally sensitive periods. Therefore, relationships between past-month binge alcohol and cannabis co-use and cognitive functioning were examined in adolescents and young adults.

methodData from the Imaging Data in Emerging Adults with Addiction (IDEAA) Consortium were used to assess cognitive functioning in emerging adults with a large range of substance use (n = 232; 15-26 years old) who were abstinent for at least 3 weeks. Multiple regressions assessed cognitive functioning by past-month binge episodes, cannabis use episodes, and same-day co-use, controlling for covariates (e.g., study site, sex, age).

resultsAfter correcting for multiple comparisons, more past-month co-use episodes were related to decreased Ruff 2&7 selective attention accuracy (p = .036). Sex significantly covaried with California Verbal Learning Test-Second Edition initial learning.

conclusionsAlthough few significant relationships were found and effect sizes are modest, the persistence of an effect on attention despite a period of sustained abstinence highlights the need to carefully investigate patterns of substance use and potential independent and interactive effects on the developing brain.

Indexed as

CognitionAdolescentAdultBinge DrinkingFemaleHumansMaleMarijuana AbuseMarijuana SmokingYoung Adult

Identifiers

PMID32800084
PMCPMC7437560
OpenAlexW3057345747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.