Evidence map›Paper›PMID 32799484›Full record

ArticleInorganic chemistry2020

A High-Denticity Chelator Based on Desferrioxamine for Enhanced Coordination of Zirconium-89.

Elaheh Khozeimeh Sarbisheh, Akam K Salih, Shvan J Raheem, Jason S Lewis, Eric W Price

Open access · greenAbstract read
In one paragraph

Article in Inorganic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

  1. The Evaluation of (1Molecules (Basel, Switzerland) · 2025
    Article
  2. From Desferrioxamine B Umpolung to an Enantiopure Bifunctional Chelator forChemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  3. Radiotheranostic landscape: A review of clinical and preclinical development.European journal of nuclear medicine and molecular imaging · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Preclinical PET and MR Evaluation ofNanomaterials (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Polyazamacrocycle Ligands FacilitateInorganic chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Elaheh Khozeimeh SarbishehDepartment of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N 5C9, Canada.
Akam K SalihDepartment of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N 5C9, Canada.
Shvan J RaheemDepartment of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N 5C9, Canada.
Jason S LewisDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.ORCID http://orcid.org/0000-0001-7065-4534
Eric W PriceDepartment of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N 5C9, Canada.ORCID http://orcid.org/0000-0002-8619-1199
University of Saskatchewan · CAMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Leveraging Pb-203/212 for the Theranostic Imaging and Therapy of Prostate CancerR35CA232130 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI LEWIS, JASON S. · 2019 to 2025
$8.2M
The Clinical PET Imaging of Metastatic Breast Cancer with Site-Specifically Labeled 89Zr-TrastuzumabR01CA204167 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI LEWIS, JASON S., ULANER, GARY ALLAN · 2016 to 2020
$3.4M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA204167NCI NIH HHS R35 CA232130
6 · The paper itself

Abstract

Herein we report a new high-denticity chelator based on the iron siderophore desferrioxamine (DFO). Our new chelator-DFO2-is acyclic and was designed and synthesized with the purpose of improving the coordination chemistry and radiolabeling performance with radioactive zirconium-89. The radionuclide zirconium-89 ([

Indexed as

Coordination ComplexesDeferoxamineDensity Functional TheoryIron Chelating AgentsZirconiumCoordination ComplexesDeferoxamineIron Chelating AgentsZirconium

Identifiers

PMID32799484
PMCPMC8293797
OpenAlexW3045827062

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.