ArticleBJOG : an international journal of obstetrics and gynaecology2020
Clinical characteristics and risk factors for mortality in obstetric patients with severe COVID-19 in Brazil: a surveillance database analysis.
Article in BJOG : an international journal of obstetrics and gynaecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.
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Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Pooled it
- Maternal death related to COVID-19: A systematic review and meta-analysis focused on maternal co-morbidities and clinical characteristics.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021Pooled it
- Gamma SARS-CoV-2 variant of concern infection repercussions on pregnancy outcomes: A translational cohort study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Factors Associated with Maternal Mortality from COVID-19 in Pernambuco, Brazil (2020-2021): A Case-Control Study.Diseases (Basel, Switzerland) · 2026Article
- Effectiveness of oseltamivir in hospitalised obstetric patients with COVID-19: a retrospective cohort study using a Brazilian national database.BMC infectious diseases · 2025Article
- A Multicentric Study on Adverse COVID-19 Outcomes Among Pregnant and Nonpregnant Women in Multidisciplinary Hospitals of Kazakhstan.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Five years after the COVID-19 pandemic began: lessons on vaccination and obstetric care in Brazil.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Article
- Mortality, intensive care unit admission, and ventilatory support in pregnant and nonpregnant women with COVID-19 in Brazil: a paired observational study.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025Observational
- Clinical characteristic and outcomes of pregnant women with COVID-19: The PROUDEST prospective cohort study.PloS one · 2025Article
- COVID-19 and pregnancy: a comprehensive study of comorbidities and outcomes.BMC public health · 2024Article
- Article
- Factors associated with hospitalizations and deaths of pregnant women from Paraná due to COVID-19: a cross-sectional study.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2024Observational
- COVID-19 threatens the progress of humanised childbirth: a qualitative study of giving birth during the pandemic in Brazil.Sexual and reproductive health matters · 2023Article
- Maternal Risk Factors Associated with Negative COVID-19 Outcomes and Their Relation to Socioeconomic Indicators in Brazil.Healthcare (Basel, Switzerland) · 2023Article
- Maternal mortality in Colombia during the COVID-19 pandemic: time series and social inequities.BMJ open · 2023Article
- Obesity during Pregnancy and SARS-CoV-2/COVID-19-Case Series of the Registry Study "COVID-19 Related Obstetric and Neonatal Outcome Study" (CRONOS-Network).Journal of clinical medicine · 2023Article
- Role of biomarkers (sFlt-1/PlGF) in cases of COVID-19 for distinguishing preeclampsia and guiding clinical management.Pregnancy hypertension · 2023Article
- Is it possible to reduce the rate of vertical transmission and improve perinatal outcomes by inclusion of remdesivir in treatment regimen of pregnant women with COVID-19?BMC pregnancy and childbirth · 2023Article
- COVID-19 Pandemic Impact on the Maternal Mortality in Kazakhstan and Comparison with the Countries in Central Asia.International journal of environmental research and public health · 2023Article
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Authors and funding
13 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe clinical characteristics of pregnant and postpartum women with severe COVID-19 in Brazil and to examine risk factors for mortality.
designCross-sectional study based on secondary surveillance database analysis.
settingNationwide Brazil. POPULATION OR SAMPLE: 978 Brazilian pregnant and postpartum women notified as COVID-19 Acute Respiratory Distress Syndrome (ARDS) cases with complete outcome (death or cure) up to 18 June 2020.
methodsData was abstracted from the Brazilian ARDS Surveillance System (ARDS-SS) database. All eligible cases were included. Data on demographics, clinical characteristics, intensive care resources use and outcomes were collected. Risk factors for mortality were examined by multivariate logistic regression.
main outcome measuresCase fatality rate.
resultsWe identified 124 maternal deaths, corresponding to a case fatality rate among COVID-19 ARDS cases in the obstetric population of 12.7%. At least one comorbidity was present in 48.4% of fatal cases compared with 24.9% in survival cases. Among women who died, 58.9% were admitted to ICU, 53.2% had invasive ventilation and 29.0% had no respiratory support. The multivariate logistic regression showed that the main risk factors for maternal death by COVID-19 were being postpartum at onset of ARDS, obesity, diabetes and cardiovascular disease, whereas white ethnicity had a protective effect.
conclusionsNegative outcomes of COVID-19 in this population are affected by clinical characteristics but social determinants of health also seem to play a role. It is urgent to reinforce containment measures targeting the obstetric population and ensure high quality care throughout pregnancy and the postpartum period. TWEETABLE ABSTRACT: A total of 124 COVID-19 maternal deaths were identified in Brazil. Symptoms onset at postpartum and comorbidities are risk factors.
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