Evidence map›Paper›PMID 32799346›Full record

ArticleHeadache2020

Employee and Employer Benefits From a Migraine Management Program: Disease Outcomes and Cost Analysis.

Leonhard Schaetz, Timo Rimner, Purnima Pathak, Juanzhi Fang, Deepak Chandrasekhar, Jelena Mueller, Peter S Sandor, Andreas R Gantenbein

Open access · hybridAbstract read
In one paragraph

Article in Headache, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Telemedicine for headache disorders in real-world practice: from patient experience to health system impact.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Migraine in the workplace.eNeurologicalSci · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Leonhard SchaetzNovartis Pharma AG, Basel, Switzerland.
Timo RimnerMedgate, Basel, Switzerland.
Purnima PathakNovartis Ireland Ltd, Dublin, Ireland.
Juanzhi FangNovartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Deepak ChandrasekharHealint Pte Ltd., Singapore, Singapore.
Jelena MuellerNovartis Pharma AG, Basel, Switzerland.
Peter S SandorNeurology & Neurorehabilitation, RehaClinic, Bad Zurzach, Switzerland.
Andreas R GantenbeinNeurology & Neurorehabilitation, RehaClinic, Bad Zurzach, Switzerland.
Novartis (Switzerland) · CHHealing Foundation · AUMedartis (Switzerland) · CHNovartis (Ireland) · IENovartis (United States) · USStiftung für Forschung in Spätantike und Mittelalter HR. Sennhauser · CHUniversity Hospital of Zurich · CH

Funding

Novartis Pharma AG, Basel, Switzerland.
6 · The paper itself

Abstract

objectiveTo assess the impact of a migraine management program offered as a complimentary service by a company within its corporate well-being program.

backgroundMigraine imposes a substantial burden on patients, families, employers, and societies. As migraine primarily affects working-age adults, this has important implications for both employees and employers. Workplace educational and well-being programs positively contribute to employees' productivity, reduce costs related to absenteeism, and improve the quality of life of the employees living with migraine.

methodsThis was a non-interventional cohort study, which followed employees and their family members over time. Participants received 1 telemedicine consultation to determine migraine diagnosis or a high probability of having migraine and 6 sessions of individualized telecoaching from a specialized nurse via a specially developed smartphone application to optimize their migraine management leveraging all appropriate medical and lifestyle options. Participants were evaluated during the program and at 3 months after completion through a series of validated questionnaires including Migraine Disability Assessment (MIDAS), Patient Activation Measure (PAM), and satisfaction with the services offered. A cost analysis was also performed to determine the economic benefit of the program considering the number of completers, dropouts, their associated program costs, MIDAS data, average salary of a Swiss employee in the pharma sector, and working days per year.

resultsOf the 141 participants enrolled in the program, 79 completed 6-month and 42 completed 9-month assessments. The total MIDAS scores (mean, standard deviation [SD]) significantly improved from baseline by 54% at Month 6 (15.0 [13.6] vs 6.9 [8.2]; mean [SD] reduction: 8.1 [12.9], 95% confidence interval [CI]: 5.6-10.6; P < .0001) and by 64% at Month 9 (15.4 [14.7] vs 5.6 [6.0]; mean [SD] reduction: 9.8 [14.0], 95% CI: 6.6-13.0; P < .0001). The PAM scores also significantly improved from baseline by 8% at Month 6 (63.8 [10.9] vs 69.6 [12.8]; mean [SD] increase: 5.8 [12.8], 95% CI: 3.2-8.4; P = .003) and 11% at Month 9 (63.5 [10.7] vs 71.3 [12.2]; mean [SD] increase: 7.8 [11.0], 95% CI: 4.3-11.2; P = .003). At Month 6, common coaching lessons and respective action plans focused on progressive muscle relaxation, sleep, hydration, nutrition, general disease education, and stress management. The exit survey showed that the majority of the participants who completed the program had a meaningful and sustained improvement in their overall health and reported a high level of satisfaction with the program. The cost analysis revealed that on average participants gained 10.8 (95% CI: 9.3-12.3) working days/year that were previously lost due to migraine, resulting in a positive return on investment (ROI) of 490% (95% CI: 410%-570%), indicating a higher magnitude of savings that could be achieved by the implementation of such program. In addition to ROI and work productivity gained, participants also gained on average 13.6 (95% CI: 9.9-17.3) migraine-free days/year for their private and social life.

conclusionThe employer-sponsored disease management program provided a better understanding of migraine, promoted methods and approaches to improve management by combining medical and lifestyle options leading to significant improvements in migraine symptoms that sustained beyond the intervention, supporting prolonged effectiveness of such programs. The program also provided a high ROI to the employer, supporting that the systematic inclusion of such programs into corporate well-being initiatives can be of significant benefit not only to the impacted individuals but to the employers as well.

Indexed as

Costs and Cost AnalysisDisease ManagementEmploymentOutcome Assessment, Health CareProgram DevelopmentTelemedicineAdolescentAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedMigraine DisordersPersons with Disabilitiesdisease management programmigraineMigraine Disability Assessmentparticipants’ satisfactionPatient Activation Measurereturn on investment

Identifiers

PMID32799346
PMCPMC7589238
OpenAlexW3049374595

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.