ReviewTransfusion2020
Risk of transmission of severe acute respiratory syndrome coronavirus 2 by transfusion: A literature review.
Review in Transfusion, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Solid organ transplantation from donors with recent or current SARS-CoV-2 infection: A systematic review.Anaesthesia, critical care & pain medicine · 2022Pooled it
- The role of convalescent plasma and hyperimmune immunoglobulins in the COVID-19 pandemic, including implications for future preparedness.Frontiers in immunology · 2024Review
- COVID-19 in a Portuguese whole blood donor population.Heliyon · 2023Article
- Article
- Comparison of Levels of Nasal, Salivary, and Plasma Antibody to Severe Acute Respiratory Syndrome Coronavirus 2 During Natural Infection and After Vaccination.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Allogeneic hematopoietic stem cell transplantation in the COVID-19 era.Frontiers in immunology · 2023Review
- Transplanting COVID-19 positive donors: Expanding our experience to widen the donor pool.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2022Article
- Lessons Learned from the COVID-19 Pandemic and How Blood Operators Can Prepare for the Next Pandemic.Viruses · 2022Review
- Frequent detection but lack of infectivity of SARS-CoV-2 RNA in presymptomatic, infected blood donor plasma.The Journal of clinical investigation · 2022Article
- SARS-CoV-2 and post-donation information: a one-year experience of the French haemovigilance network.Blood transfusion = Trasfusione del sangue · 2022Article
- Lung donation and SARS-CoV-2 transmission: Missed detection versus missed opportunity?Immunity, inflammation and disease · 2022Article
- Insights into the immune responses of SARS-CoV-2 in relation to COVID-19 vaccines.Journal of microbiology (Seoul, Korea) · 2022Review
- Legume Lectins with Different Specificities as Potential Glycan Probes for Pathogenic Enveloped Viruses.Cells · 2022Review
- Reinfection With SARS-CoV-2: Implications for Vaccines.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Review
- The Impact of COVID-19 on Blood Transfusion Services: A Systematic Review and Meta-Analysis.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2021Article
- SARS-CoV-2 seroprevalence among blood donors in Québec, and analysis of symptoms associated with seropositivity: a nested case-control study.Canadian journal of public health = Revue canadienne de sante publique · 2021Article
- Impact of pathogen reduction methods on immunological properties of the COVID-19 convalescent plasma.Vox sanguinis · 2021Article
- Pathophysiology of infection with SARS-CoV-2-What is known and what remains a mystery.Respirology (Carlton, Vic.) · 2021Review
- Review
- COVID-19 re-infection in Shahroud, Iran: a follow-up study.Epidemiology and infection · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel human coronavirus responsible for coronavirus disease 2019 (COVID-19). The emergence of this virus in Wuhan, China, at the end of 2019 and its worldwide spread to reach the pandemic stage has raised concerns about the possible risk that it might be transmissible by transfusion. This theoretical risk is further supported by reports of the detection of viral RNA in the blood of some infected individuals. To further address this risk, a thorough PubMed literature search was performed to systematically identify studies reporting data on the detection of SARS-CoV-2 RNA in blood or its components. Complementary searches were done to identify articles reporting data on the in vitro infectivity of blood components. At least 23 articles presenting data on the detection of SARS-CoV-2 RNA in blood, plasma, or serum were identified. Of these, three studies reported on blood donors with COVID-19 infection identified after donation, and no cases of transfusion transmission were identified. A few studies mentioned results of in vitro infectivity assays of blood components in permissive cell lines, none of which were able to detect infectious virus in blood or its components. Complementary searches have identified reports demonstrating that the correlation between the presence of viral RNA in a biologic sample and infectivity requires a minimal RNA load, which is rarely, if ever, observed in blood components. Overall, the available evidence suggests that the risk of transmission of SARS-CoV-2 by transfusion remains theoretical.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.