ReviewNeuroscience bulletin2020
Miniature Fluorescence Microscopy for Imaging Brain Activity in Freely-Behaving Animals.
Review in Neuroscience bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- Focus-tunable two-photon fiberscope enablingOptics letters · 2025Article
- Integrating Optics and Parametrically-Resonant Micro-Scanner Design for Large Working Distance Implantable Microscopy.IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division · 2025Article
- Wide-field fluorescence navigation system for efficient miniature multiphoton imaging in freely behaving animals.Neurophotonics · 2025Article
- Deep learning enhanced light sheet fluorescence microscopy for in vivo 4D imaging of zebrafish heart beating.Light, science & applications · 2025Article
- Tetherless miniaturized point detector device for monitoring cortical surface hemodynamics in mice.Journal of biomedical optics · 2025Article
- Window into the Brain: In Vivo Multiphoton Imaging.ACS photonics · 2025Review
- Multimode fiber endoscopes for computational brain imaging.Neurophotonics · 2024Article
- Trans-segmental imaging in the spinal cord of behaving mice.Nature biotechnology · 2023Article
- Multiplex translaminar imaging in the spinal cord of behaving mice.Nature communications · 2023Article
- Overcoming the field-of-view to diameter trade-off in microendoscopy via computational optrode-array microscopy.Optics express · 2023Article
- Visualizing Seizure Propagation in Freely-moving Mice via Miniature Two-photon Microscopy.Neuroscience bulletin · 2022Article
- Volumetric Imaging of Neural Activity by Light Field Microscopy.Neuroscience bulletin · 2022Review
- Toolbox for studying neurovascular couplingNeurophotonics · 2022Review
- MouseVenue3D: A Markerless Three-Dimension Behavioral Tracking System for Matching Two-Photon Brain Imaging in Free-Moving Mice.Neuroscience bulletin · 2022Article
- Scan-less machine-learning-enabled incoherent microscopy for minimally-invasive deep-brain imaging.Optics express · 2022Article
- Advances of optical miniscopes forFrontiers in neuroscience · 2022Review
- Neurophotonic tools for microscopic measurements and manipulation: status report.Neurophotonics · 2022Article
- Multiphoton intravital microscopy of rodents.Nature reviews. Methods primers · 2022Article
- Advanced high resolution three-dimensional imaging to visualize the cerebral neurovascular network in stroke.International journal of biological sciences · 2022Review
- Miniature two-photon microscopy for enlarged field-of-view, multi-plane and long-term brain imaging.Nature methods · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An ultimate goal of neuroscience is to decipher the principles underlying neuronal information processing at the molecular, cellular, circuit, and system levels. The advent of miniature fluorescence microscopy has furthered the quest by visualizing brain activities and structural dynamics in animals engaged in self-determined behaviors. In this brief review, we summarize recent advances in miniature fluorescence microscopy for neuroscience, focusing mostly on two mainstream solutions - miniature single-photon microscopy, and miniature two-photon microscopy. We discuss their technical advantages and limitations as well as unmet challenges for future improvement. Examples of preliminary applications are also presented to reflect on a new trend of brain imaging in experimental paradigms involving body movements, long and complex protocols, and even disease progression and aging.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.