Evidence map›Paper›PMID 32797383›Full record

ArticleInternational urology and nephrology2020

Effects of 12 months of detraining on health-related quality of life in patients receiving hemodialysis therapy.

Clara Suemi Costa Rosa, Christoforos D Giannaki, Argyro Krase, Meropi Mplekou, Stefania S Grigoriou, Ioannis Stefanidis, Eleftherios Lavdas, Aggelos Pappas, Saul Bloxham, Christina Karatzaferi and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in International urology and nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07780175 (The Effects of Long-Term Hybrid Intradialytic Exercise on Cognitive Function and Quality of Life in End-Stage Kidney Disease Patients), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07780175 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

The Effects of Long-Term Hybrid Intradialytic Exercise on Cognitive Function and Quality of Life in End-Stage Kidney Disease Patients: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of ThessalyRan2026 to 2027Enrolled60ConditionsSupportive Care, Exercise Adaptations, Exercise Training Therapy, Clinical ExerciseArmsResistance Training, Aerobic training, Combination Training
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Quality of life and functional capacity in depressive patients on hemodialysis: a systematic review and meta-analysis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Clara Suemi Costa RosaBioscience Institute, Sao Paulo State University, Rio Claro, Brazil.
Christoforos D GiannakiDepartment of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.
Argyro KraseDepartment of PE and Sport Science, University of Thessaly, Trikala, Greece.
Meropi MplekouDepartment of PE and Sport Science, University of Thessaly, Trikala, Greece.
Stefania S GrigoriouDepartment of PE and Sport Science, University of Thessaly, Trikala, Greece.
Ioannis StefanidisDepartment of Medicine, School of Health Science, University of Thessaly, Larissa, Greece.
Eleftherios LavdasDepartment of Biomedical Sciences, University of West Attica, Athens, Greece.
Aggelos PappasDepartment of PE and Sport Science, University of Thessaly, Trikala, Greece.
Saul BloxhamSchool of Sports, Health and Wellbeing, Plymouth Marjon University, Plymouth, UK.
Christina KaratzaferiDepartment of PE and Sport Science, University of Thessaly, Trikala, Greece.
Giorgos K SakkasDepartment of PE and Sport Science, University of Thessaly, Trikala, Greece. gsakkas@uth.gr.ORCID http://orcid.org/0000-0002-2462-995X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLimited data exist regarding the effects of detraining on functional capacity and quality of life (QoL) in the hemodialysis population. The aim of the current study was to assess whether the discontinuation from a systematic intradialytic exercise training program will affect aspects of health-related QoL and functional capacity in hemodialysis patients.

methodsSeventeen hemodialysis patients (12 Males/5 Females, age 60.8 ± 13.6 year) participated in this study. Patients were assessed for functional capacity using various functional capacity tests while QoL, daily sleepiness, sleep quality, depression and fatigue were assessed using validated questionnaires at the end of a 12-month aerobic exercise program and after 12 months of detraining.

resultsThe detraining significantly reduced patients' QoL score by 20% (P = 0.01). More affected were aspects related to the physical component summary of the QoL (P < 0.001) rather than those related to the mental one (P = 0.096). In addition, the performance in the functional capacity tests was reduced (P < 0.05), while sleep quality (P = 0.020) and daily sleepiness scores (P = 0.006) were significantly worse after the detraining period. Depressive symptoms (P = 0.214) and the level of fatigue (P = 0.163) did not change significantly.

conclusionsDetraining has a detrimental effect in patients' QoL, functional capacity and sleep quality. The affected physical health contributed significantly to the lower QoL score. It is crucial for the chronic disease patients, even during emergencies such as lockdowns and restrictions in activities to maintain a minimum level of activity to preserve some of the acquired benefits and maintain their health status.

Indexed as

ExerciseQuality of LifeRenal DialysisAgedFemaleHumansKidney Failure, ChronicMaleMiddle AgedTime FactorsDetrainingExercise trainingHemodialysisQuality of life

Identifiers

PMID32797383
PMCPMC7426199

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.