Trial reportDigestive diseases and sciences2021
Endoscopic Closure Utilizing Endoloop and Endoclips After Gastric Endoscopic Submucosal Dissection for Patients on Antithrombotic Therapy.
Trial report in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Potential of Direct Oral Anticoagulant in Bleeding After Gastric Endoscopic Submucosal Dissection: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2024Pooled it
- The Hedgehog Method Following Gastric Endoscopic Submucosal Dissection: Observed Postoperative Bleeding Rates Across BEST-J Risk Categories.Digestive diseases and sciences · 2026Article
- The Effect of Nexpowder in Reducing Post-ESD Coagulation Syndrome in Proximal Colon Lesions: A Retrospective Multicenter Study.Journal of gastroenterology and hepatology · 2026Article
- Feasibility of Zeosuture M for gastric endoscopic submucosal dissection defect closure during anticoagulation: a preclinical porcine study from Japan.Clinical endoscopy · 2026Article
- Effect of Oral Proton-Pump Inhibitor Administration on Reducing the Delayed Bleeding Risk in 5 Upper Gastrointestinal Endoscopic Treatments.The American journal of gastroenterology · 2026Article
- Article
- Review
- Feasibility of Endoscopic Closure Method Using Low Cost Clips With Thread for Post Gastric Endoscopic Submucosal Dissection: A Pilot Study.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Effectiveness of the aspiration method in preventing delayed bleeding after gastric endoscopic submucosal dissection.Surgical endoscopy · 2026Article
- High Rates of Defect Closure After Resection of Large Nonpedunculated Colorectal Lesions Using a Through-The-Scope Clip With Anchor Prongs.United European gastroenterology journal · 2026Observational
- A Novel Flexible Endoscopic C-shaped Suturing Device for Gastrointestinal Wound Closure: First Survival Study in Pigs (With Video).Endoscopy international open · 2026Article
- Recent Advances in Endoscopic Submucosal Dissection for Gastric Cancer: Focusing on Expanded Indications and Technological Innovations.Journal of gastric cancer · 2026Review
- Feasibility, Stability, and Clinical Outcomes of Mucosal Defect Closure Using a Novel Hooking-Jaw Clip after Gastric Endoscopic Submucosal Dissection.Endoscopy international open · 2026Article
- Dual-function robotic gripper for traction and closure in gastric endoscopic submucosal dissection: an in vivo porcine model study (with video).Surgical endoscopy · 2025Article
- Effect of Defect Closure on Delayed Bleeding in Gastric Endoscopic Submucosal Dissection: A Single Center Experience.Digestive diseases and sciences · 2025Article
- Impact of gastric neoplasms location on clinical outcome of patients treated by endoscopic submucosal dissection.World journal of gastrointestinal endoscopy · 2025Article
- The competency of the novel through-the-scope suture device for gastric mucosal defects: In vivo study in a porcine model (with video).DEN open · 2025Article
- Closure strength of endoscopic hand-suturing in ex vivo porcine gastric ESD defect models: an exploratory animal study.Surgical endoscopy · 2025Article
- Unique closure of large colonic endoscopic submucosal dissection defect using zigzag clip with line pulley securing technique.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025Article
- Endoscopic closure using a dedicated device following gastric endoscopic submucosal dissection: Multicenter, prospective, observational pilot study.Endoscopy international open · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAntithrombotic therapy is a well-known independent risk factor for bleeding after endoscopic submucosal dissection (ESD) of early gastric cancer (EGC). A novel method of ulcer base closure using an endoloop and endoclips has been reported. This study aimed to evaluate the effectiveness of endoscopic closure using an endoloop and endoclips in preventing post-ESD bleeding in patients undergoing gastric ESD on antithrombotic therapy.
methodsThis was a single center, retrospective study. Patients on antithrombotic therapy who underwent gastric ESD were divided into two groups, the closure group and the non-closure group. We analyzed procedural outcomes, post-ESD bleeding rate and factors associated with post-ESD bleeding.
resultsAmong 400 ESDs with EGCs in 311 patients, 131 ESDs in 110 patients were in the closure group, and 269 ESDs in 217 patients were in the non-closure group (16 patients were overlapped in both groups). Post-ESD bleeding rate was 11.5% (15/131) in the closure group, and 11.9% (32/269) in the non-closure group (p = 0.89). Total sustained closure rate during second look endoscopy was 47.8% (33/69). Post-ESD bleeding rate tended to be lower in the closure group than in the non-closure group for lesions located in the greater curvature (3.6% vs. 11.1%, p = 0.11). In addition, sustained closure rate was significantly higher in the greater curvature than in the lesser curvature (72.0% vs. 34.1%, p < 0.01). Multivariate analysis revealed resection size > 40 mm and heparin bridge were the independent risk factor for post-ESD bleeding.
conclusionUlcer base closure using endoloop and endoclips did not prevent post-ESD bleeding in patients on antithrombotic therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.