Evidence map›Paper›PMID 32797307›Full record

ArticleEJNMMI research2020

Reliability of dopamine transporter PET measurements with [

Vera S Kerstens, Patrik Fazio, Mathias Sundgren, Granville J Matheson, Erika Franzén, Christer Halldin, Simon Cervenka, Per Svenningsson, Andrea Varrone

Open access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Sertraline treatment influences [EJNMMI research · 2023
    Article
  4. [EJNMMI research · 2023
    Article
  5. Article
  6. Validation of dynamic [EJNMMI research · 2022
    Article
  7. [EJNMMI research · 2022
    Article
  8. Novel Tracers and Radionuclides in PET Imaging.Radiologic clinics of North America · 2021
    Review
  9. Biomedicines · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Vera S KerstensCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Karolinska University Hospital, Stockholm, Sweden. vera.kerstens@ki.se.ORCID http://orcid.org/0000-0002-5770-8419
Patrik FazioCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Karolinska University Hospital, Stockholm, Sweden.
Mathias SundgrenDepartment of Clinical Neuroscience, Division of Neuro, Karolinska Institutet, Stockholm, Sweden.
Granville J MathesonCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Karolinska University Hospital, Stockholm, Sweden.
Erika FranzénDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.
Christer HalldinCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Karolinska University Hospital, Stockholm, Sweden.
Simon CervenkaCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Karolinska University Hospital, Stockholm, Sweden.
Per SvenningssonDepartment of Clinical Neuroscience, Division of Neuro, Karolinska Institutet, Stockholm, Sweden.
Andrea VarroneCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Karolinska University Hospital, Stockholm, Sweden.
Karolinska University Hospital · SE

Funding

Åhlén-stiftelsen mA4/h17Karolinska Institutet 2016-00186Vetenskapsrådet (SE) 2016-02607Vetenskapsrådet (SE) 523-2014-3467
6 · The paper itself

Abstract

backgroundReliable quantification of dopamine transporter (DAT), a biomarker for Parkinson's disease (PD), is essential for diagnostic purposes as well as for evaluation of potential disease-modifying treatment. Due to degeneration of dopaminergic neurons and thus lower expected radioligand binding to DAT, higher measurement variability in PD patients might be expected than earlier reproducibility results in healthy controls. Therefore, we aimed to examine the test-retest properties of [

methodsNine patients with PD (Hoehn and Yahr stage < 3) were included (men/women 6/3; mean age 65.2 ± 6.8 years). Each patient underwent two [

results[

conclusionDAT-PET measurements with [

trial registrationEudraCT 2017-003327-29.

Indexed as

[18F]FE-PE2IDopamine transporterParkinson’s diseaseReliabilityTest-retest

Identifiers

PMID32797307
PMCPMC7427674
OpenAlexW3049254927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.