Evidence map›Paper›PMID 32797193›Full record

ArticleJournal of vision2020

Test-retest of a phoria adaptation stimulus-induced functional MRI experiment.

Cristian Morales, Suril Gohel, Mitchell Scheiman, Xiaobo Li, Elio M Santos, Ayushi Sangoi, Tara L Alvarez

Open access · goldAbstract read
In one paragraph

Article in Journal of vision, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Functional magnetic resonance imaging activation for different vergence eye movement subtypes.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Cristian MoralesBiomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Suril GohelDepartment of Health Informatics, Rutgers University School of Health Professions, Newark, NJ, USA.
Mitchell ScheimanPennsylvania College of Optometry, Salus University, Philadelphia, PA, USA.
Xiaobo LiBiomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Elio M SantosBiomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Ayushi SangoiBiomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Tara L AlvarezBiomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
New Jersey Institute of Technology · USNIIT (India) · INRutgers, The State University of New Jersey · USSalus University · US

Funding

Functional Mechanisms of Neural Control in Convergence InsufficiencyR01EY023261 · NEI · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI ALVAREZ, TARA LYNN · 2014 to 2025
$4.9M
NEI NIH HHS R01 EY023261
6 · The paper itself

Abstract

This study was designed to identify the neural substrates activated during a phoria adaptation task using functional magnetic resonance imaging (MRI) in young adults with normal binocular vision and to test the repeatability of the fMRI measurements for this protocol. The phoria adaptation task consisted of a block protocol of 90 seconds of near visual crossed fixation followed by 90 seconds of far visual uncrossed fixation, repeated three times; the data were collected during two different experimental sessions. Results showed that the oculomotor vermis, cuneus, and primary visual cortex had the greatest functional activity within the regions of interest studied when stimulated by the phoria adaptation task. The oculomotor vermis functional activity had an intraclass correlation coefficient (ICC) of 0.3, whereas the bilateral cuneus and primary visual cortex had good ICC results of greater than 0.6. These results suggest that the sustained visual fixation task described within this study reliably activates the neural substrates of phoria adaptation. This protocol establishes a methodology that can be used in future longitudinal studies investigating therapeutic interventions that may modify phoria adaptation.

Indexed as

Adaptation, OcularAdolescentAdultBrainBrain MappingFemaleFixation, OcularHumansMagnetic Resonance ImagingMaleStrabismusVision, BinocularYoung Adult

Identifiers

PMID32797193
PMCPMC7438664
OpenAlexW3049286330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.