Evidence map›Paper›PMID 32797097›Full record

ArticlePloS one2020

RETRACTED: Biogenic green synthesis of MgO nanoparticles using Saussurea costus biomasses for a comprehensive detection of their antimicrobial, cytotoxicity against MCF-7 breast cancer cells and photocatalysis potentials.

Musarat Amina, Nawal M Al Musayeib, Nawal A Alarfaj, Maha F El-Tohamy, Hesham F Oraby, Gadah A Al Hamoud, Sarah I Bukhari, Nadine M S Moubayed

RetractedAbstract readRetracted Publication
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. RSC advances · 2026
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  16. Frontiers in pharmacology · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Musarat AminaDepartment of Pharmacognosy, Pharmacy College, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0003-4545-253X
Nawal M Al MusayeibDepartment of Pharmacognosy, Pharmacy College, King Saud University, Riyadh, Saudi Arabia.
Nawal A AlarfajDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Maha F El-TohamyDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Hesham F OrabyDeanship of Scientific Research, Umm Al-Qura University, Makkah, Saudi Arabia.
Gadah A Al HamoudDepartment of Pharmacognosy, Pharmacy College, King Saud University, Riyadh, Saudi Arabia.
Sarah I BukhariDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Nadine M S MoubayedDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Distinct morphological MgO nanoparticles (MgONPs) were synthesized using biomasses of Saussurea costus roots. The biomass of two varieties of Saussurea costus (Qustal hindi and Qustal bahri) were used in the green synthesis of MgONPs. The physical and chemical features of nanoparticles were confirmed by spectroscopic and microscopic techniques. The surface morphology of the obtained nanoparticles was detected at different magnifications by SEM and TEM microscopy and the size of nanoparticles were found to be 30 and 34 nm for Qustal hindi and Qustal bahri, respectively. The antimicrobial activity of the prepared MgONPs was screened against six pathogenic strains. The synthesized nanoparticles by Qustal bahri biomass exerted significant inhibition zones 15, 16, 18, 17, 14, and 10 mm against E. coli, P. aeruginosa, C. tropicalis and C. glabrata, S. aureus and B. subtilis as compared to those from Qustal hindi 12, 8 and 17 mm against B. subtilis, E. coli and C. tropicalis, respectively. MgONPs showed a potential cytotoxicity effect against MCF-7 breast cancer cell lines. Cellular investigations of MgONPs revealed that the prepared nanoparticles by Qustal bahri exhibited high cytotoxicity against MCF-7 cancer cell lines. IC50 values in MCF-7 cells were found to be 67.3% and 52.1% for MgONPs of Saussurea costus biomasses, respectively. Also, the photocatalytic activity of MgONPs of each Saussurea costus variety was comparatively studied. They exhibited an enhanced photocatalytic degradation of methylene blue after UV irradiation for 1 h as 92% and 59% for those prepared by Qustal bahri and Qustal hindi, respectively. Outcome of results revealed that the biosynthesized MgONPs showed promising biomedical potentials.

Indexed as

Anti-Infective AgentsAntineoplastic AgentsBacteriaBiomassBreast NeoplasmsCatalysisCell ProliferationCell SurvivalFemaleFungiGreen Chemistry TechnologyHumansMagnesium OxideMCF-7 CellsMetal NanoparticlesMethylene BlueAnti-Infective AgentsAntineoplastic AgentsMagnesium OxideMethylene BluePlant Extracts

Identifiers

PMID32797097
PMCPMC7428194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.