SynthesisInternational journal of obesity (2005)2020
Ultra-processed food and the risk of overweight and obesity: a systematic review and meta-analysis of observational studies.
Synthesis in International journal of obesity (2005), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 209 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
209 citing papers in PubMed, 13 syntheses or guidelines pooled it.
- Health Effects of Plant-Based Diets in People with Overweight or Obesity: A Systematic Review and Meta-Analysis.Nutrients · 2026Pooled it
- Ultra-processed food consumption and the risk of overweight and obesity in adolescents: A systematic review and meta-analysis.PloS one · 2026Pooled it
- Ultra-Processed Food Intakes and Health Outcomes in Adults Older Than 60 Years: A Systematic Review.Nutrition reviews · 2025Pooled it
- Consumption of fast foods and ultra-processed foods and breast cancer risk: a systematic review and meta-analysis.Global health research and policy · 2025Pooled it
- Ultra-processed foods and non-alcoholic fatty liver disease: an updated systematic review and dose-response meta-analysis.Frontiers in nutrition · 2025Pooled it
- Prevention of Obesity among Adults: Evidence- and Consensus-Based Guideline.Obesity facts · 2025Guideline
- Association between ultraprocessed foods consumption, eating disorders, food addiction and body image: a systematic review.BMJ open · 2024Pooled it
- High intake of ultra-processed food is associated with dementia in adults: a systematic review and meta-analysis of observational studies.Journal of neurology · 2024Pooled it
- Ultra-processed food consumption and chronic kidney disease risk: a systematic review and dose-response meta-analysis.Frontiers in nutrition · 2024Pooled it
- Effects of spicy food consumption on overweight/obesity, hypertension and blood lipids in China: a meta-analysis of cross-sectional studies.Nutrition journal · 2023Pooled it
- Ultra-Processed Food Intake Is Associated with Non-Alcoholic Fatty Liver Disease in Adults: A Systematic Review and Meta-Analysis.Nutrients · 2023Pooled it
- Association between ultra-processed food consumption and risk of breast cancer: a systematic review and dose-response meta-analysis of observational studies.Frontiers in nutrition · 2023Pooled it
- Cardiovascular safety of long-term anti-obesity drugs in subjects with overweight or obesity: a systematic review and meta-analysis.European journal of clinical pharmacology · 2021Pooled it
- Satiety responsiveness following dietary exposure to ultra-processed foods differing in texture-derived eating rate: a secondary analysis of a randomized controlled crossover diet intervention.European journal of nutrition · 2026Trial
- Eating rate has sustained effects on energy intake from ultraprocessed diets: a 2-week ad libitum dietary randomized controlled crossover trial.The American journal of clinical nutrition · 2026Trial
- "Warning: ultra-processed": an online experiment examining the impact of ultra-processed warning labels on consumers' product perceptions and behavioral intentions.The international journal of behavioral nutrition and physical activity · 2024Trial
- Isocaloric replacement of ultraprocessed foods was associated with greater weight loss in the POUNDS Lost trial.Obesity (Silver Spring, Md.) · 2024Trial
- One Anastomosis Gastric Bypass versus Roux-en-Y Gastric Bypass: A Randomized Prospective Trial.Medicina (Kaunas, Lithuania) · 2024Trial
- Ultra-processed food consumption and BMI-Z among children at risk for obesity from low-income households.Pediatric obesity · 2023Trial
- Front-of-Package Labels on Unhealthy Packaged Foods in India: Evidence from a Randomized Field Experiment.Nutrients · 2022Trial
149 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNumerous studies have reported the association of ultra-processed foods with excess body weight; however, the nature and extent of this relation has not been clearly established. This systematic review was conducted to analyze the currently documented evidence regarding the association between ultra-processed food with overweight and obesity.
methodsA literature search was performed using multiple literature databases for relevant articles published prior to November 2019. Random effects model, namely the DerSimonian-Laird method, was applied to pool effect sizes. The potential sources of heterogeneity across studies were explored using the Cochrane Q test.
resultsFourteen studies (one cohort study and thirteen cross-sectional studies) were included in this review. A significant association was identified between ultra-processed food intake and overweight (pooled effect size: 1.02; 95% confidence interval (95% CI): 1.01, 1.03, p < 0.001) and obesity (pooled effect size: 1.26; 95% CI: 1.13, 1.41, p < 0.001).
conclusionOur findings revealed a positive association between ultra-processed foods and excess body weight. Future studies with longitudinal designs and adequate control for confounding factors are required to clarify whether ultra-processed food intake alters anthropometric parameters and leads to obesity.
Indexed as
Identifiers
32796919What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.