Evidence map›Paper›PMID 32796700›Full record

ArticleInternational journal of molecular sciences2020

Decreased Expression of

Andrea Balogh, Lilla Reiniger, Szabolcs Hetey, Peter Kiraly, Eszter Toth, Katalin Karaszi, Kata Juhasz, Zsolt Gelencser, Agnes Zvara, Andras Szilagyi and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Andrea BaloghSystems Biology of Reproduction Research Group, Institute of Enzymology, Research Centre for Natural Sciences, H-1117 Budapest, Hungary.
Lilla ReinigerFirst Department of Pathology and Experimental Cancer Research, Semmelweis University, H-1085 Budapest, Hungary.
Szabolcs HeteySystems Biology of Reproduction Research Group, Institute of Enzymology, Research Centre for Natural Sciences, H-1117 Budapest, Hungary.
Peter KiralySystems Biology of Reproduction Research Group, Institute of Enzymology, Research Centre for Natural Sciences, H-1117 Budapest, Hungary.
Eszter TothSystems Biology of Reproduction Research Group, Institute of Enzymology, Research Centre for Natural Sciences, H-1117 Budapest, Hungary.
Katalin KarasziSystems Biology of Reproduction Research Group, Institute of Enzymology, Research Centre for Natural Sciences, H-1117 Budapest, Hungary.ORCID 0000-0002-9188-1987
Kata JuhaszSystems Biology of Reproduction Research Group, Institute of Enzymology, Research Centre for Natural Sciences, H-1117 Budapest, Hungary.
Zsolt GelencserSystems Biology of Reproduction Research Group, Institute of Enzymology, Research Centre for Natural Sciences, H-1117 Budapest, Hungary.
Agnes ZvaraLaboratory of Functional Genomics, Department of Genetics, Biological Research Centre, H-6726 Szeged, Hungary.
Andras SzilagyiSystems Biology of Reproduction Research Group, Institute of Enzymology, Research Centre for Natural Sciences, H-1117 Budapest, Hungary.ORCID 0000-0002-1773-6861
Laszlo G PuskasLaboratory of Functional Genomics, Department of Genetics, Biological Research Centre, H-6726 Szeged, Hungary.
Janos MatkoDepartment of Immunology, Eotvos Lorand University, H-1117 Budapest, Hungary.
Zoltan PappMaternity Private Clinic, H-1126 Budapest, Hungary.
Ilona KovalszkyFirst Department of Pathology and Experimental Cancer Research, Semmelweis University, H-1085 Budapest, Hungary.
Csaba JuhaszDepartment of Pediatrics, Neurology, Neurosurgery, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Nandor Gabor ThanSystems Biology of Reproduction Research Group, Institute of Enzymology, Research Centre for Natural Sciences, H-1117 Budapest, Hungary.
Institute of Molecular Life Sciences · HUSemmelweis University · HUHUN-REN Szegedi Biológiai Kutatóközpont · HUEötvös Loránd University · HUWayne State University · US

Funding

Hungarian Scientific Research Fund K124862Hungarian Scientific Research Fund K128262Magyar Tudományos Akadémia Momentum LP2014-7/2014Magyar Tudományos Akadémia Premium_2019-436Magyar Tudományos Akadémia Young Research FellowshipsNemzeti Kutatási Fejlesztési és Innovációs Hivatal FIEK_16-1-2016-0005Nemzeti Kutatási Fejlesztési és Innovációs Hivatal VEKOP-2.3.3-15-2017-0014
6 · The paper itself

Abstract

Zinc finger protein 554 (ZNF554), a member of the Krüppel-associated box domain zinc finger protein subfamily, is predominantly expressed in the brain and placenta in humans. Recently, we unveiled that ZNF554 regulates trophoblast invasion during placentation and its decreased expression leads to the early pathogenesis of preeclampsia. Since ZNF proteins are immensely implicated in the development of several tumors including malignant tumors of the brain, here we explored the pathological role of ZNF554 in gliomas.

Indexed as

Gene Expression Regulation, NeoplasticSignal TransductionAdolescentAdultAgedBrain NeoplasmsCell Cycle CheckpointsCell Line, TumorCell ProliferationFemaleGenome, HumanGliomaHumansKruppel-Like Transcription FactorsMaleMiddle AgedKruppel-Like Transcription FactorsRNA, MessengerZNF554 protein, humanglioblastomagliomasurvivaltranscriptomezinc finger protein

Identifiers

PMID32796700
PMCPMC7461028
OpenAlexW3048755924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.