Evidence map›Paper›PMID 32796597›Full record

ArticleCancers2020

High Throughput Molecular Characterization of Normal Karyotype Acute Myeloid Leukemia in the Context of the Prospective Trial 02/06 of the Northern Italy Leukemia Group (NILG).

Silvia Salmoiraghi, Roberta Cavagna, Pamela Zanghì, Chiara Pavoni, Anna Michelato, Ksenija Buklijas, Lara Elidi, Tamara Intermesoli, Federico Lussana, Elena Oldani and 19 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 15 institutions in 1 country.

Silvia SalmoiraghiHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.
Roberta CavagnaHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.ORCID 0000-0003-4353-2210
Pamela ZanghìHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.ORCID 0000-0001-9845-3072
Chiara PavoniHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.
Anna MichelatoHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.
Ksenija BuklijasHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.
Lara ElidiHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.
Tamara IntermesoliHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.
Federico LussanaHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.ORCID 0000-0002-6510-8616
Elena OldaniHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.
Chiara CaprioliHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.
Paola StefanoniHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.
Giacomo GianfaldoniHematology Unit, Azienda Ospedaliera Universitaria Careggi, 50134 Firenze, Italy.
Ernesta AudisioHematology Unit A.O.U. Città della Salute e della Scienza di Torino, 10126 Torino, Italy.
Elisabetta TerruzziHematology Unit, Azienda Ospedaliera San Gerardo, 20900 Monza, Italy.
Lorella De PaoliHematology Unit, Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, 15121 Alessandria, Italy.
Erika BorlenghiHematology Unit, ASST-Spedali Civili, 25123, Brescia, Italy.
Irene CavattoniHematology Unit, Ospedale S. Maurizio, 39100 Bolzano, Italy.
Daniele MatteiHematology Unit, Azienda Ospedaliera S.Croce e Carle di Cuneo, 12100 Cuneo, Italy.
Annamaria ScattolinHematology Unit, Ospedale dell'Angelo and SS. Giovanni e Paolo, 30174 Venezia Mestre, Italy.
Monica TajanaHematology Unit, Azienda Socio Sanitaria Territoriale (ASST) Ospedale di Cremona, 26100 Cremona, Italy.
Fabio CiceriHematology Unit, IRCSS Ospedale San Raffaele, 20132 Milano, Italy.
Elisabetta TodiscoHematology Unit, IRCCS Istituto Clinico Humanitas di Rozzano, 20089 Rozzano (MI), Italy.
Leonardo CampiottiMedicine and Surgery Department, University of Insubria, 21100 Varese, Italy.
Paolo CorradiniHematology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy.ORCID 0000-0002-9186-1353
Nicola FracchiollaHematology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Renato BassanHematology Unit, Ospedale dell'Angelo and SS. Giovanni e Paolo, 30174 Venezia Mestre, Italy.ORCID 0000-0001-8214-2894
Alessandro RambaldiHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.ORCID 0000-0002-3739-7502
Orietta SpinelliHematology Unit, Azienda Socio Sanitaria Territoriale (ASST), Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy.ORCID 0000-0003-0374-1536
Ospedale Papa Giovanni XXIII · ITOspedale dell' Angelo · ITUniversity of Milan · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo · ITAzienda Ospedaliera San Gerardo · ITAzienda Ospedaliero-Universitaria Careggi · ITAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITFondazione Humanitas per la Ricerca · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITIRCCS Ospedale San Raffaele · ITIstituti Ospitalieri di Cremona · ITOspedale di Bolzano · ITUniversity of Insubria · IT

Funding

Agenzia Italiana del Farmaco, Ministero della Salute FARM6YMY2N/2006
6 · The paper itself

Abstract

By way of a Next-Generation Sequencing NGS high throughput approach, we defined the mutational profile in a cohort of 221 normal karyotype acute myeloid leukemia (NK-AML) enrolled into a prospective randomized clinical trial, designed to evaluate an intensified chemotherapy program for remission induction.

Indexed as

Acute Myeloid Leukemiamolecular markerNGS

Identifiers

PMID32796597
PMCPMC7464263
OpenAlexW3048536107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.