Evidence map›Paper›PMID 32796517›Full record

ReviewViruses2020

Cannabinoid-Induced Immunomodulation during Viral Infections: A Focus on Mitochondria.

Cherifa Beji, Hamza Loucif, Roman Telittchenko, David Olagnier, Xavier Dagenais-Lussier, Julien van Grevenynghe

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. CanHeliyon · 2021
    Review
  11. Review
  12. Ayu
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Cherifa BejiInstitut National de la Recherche Scientifique (INRS)-Armand-Frappier Santé Biotechnologie, 531 Boulevard des Prairies, Laval, QC H7V 1B7, Canada.
Hamza LoucifInstitut National de la Recherche Scientifique (INRS)-Armand-Frappier Santé Biotechnologie, 531 Boulevard des Prairies, Laval, QC H7V 1B7, Canada.ORCID 0000-0002-2646-524X
Roman TelittchenkoInstitut National de la Recherche Scientifique (INRS)-Armand-Frappier Santé Biotechnologie, 531 Boulevard des Prairies, Laval, QC H7V 1B7, Canada.
David OlagnierResearch Center for Innate Immunology, Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
Xavier Dagenais-LussierInstitut National de la Recherche Scientifique (INRS)-Armand-Frappier Santé Biotechnologie, 531 Boulevard des Prairies, Laval, QC H7V 1B7, Canada.ORCID 0000-0002-3004-849X
Julien van GrevenyngheInstitut National de la Recherche Scientifique (INRS)-Armand-Frappier Santé Biotechnologie, 531 Boulevard des Prairies, Laval, QC H7V 1B7, Canada.
Institut National de la Recherche Scientifique · CAAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review examines the impact of cannabinoids on viral infections, as well as its effects on the mitochondria of the nervous and immune system. The paper conveys information about the beneficial and negative impacts of cannabinoids on viral infections, especially HIV-1. These include effects on the inflammatory response as well as neuroprotective effects. We also explore non-apoptotic mitochondrial pathways modulated by the activity of cannabinoids, resulting in modifications to cellular functions. As a large part of the literature derives from studies of the nervous system, we first compile the information related to mitochondrial functions in this system, particularly through the CB1 receptor. Finally, we reflect on how this knowledge could complement what has been demonstrated in the immune system, especially in the context of the CB2 receptor and Ca

Indexed as

ImmunomodulationAnimalsCannabinoidsHumansImmune SystemMiceMitochondriaNervous SystemReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Virus DiseasesCannabinoidsReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2cannabinoidimmunityinflammationmetabolismmitochondrianervous systemTHCviral infection

Identifiers

PMID32796517
PMCPMC7472050
OpenAlexW3047964401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.