Evidence map›Paper›PMID 32796163›Full record

ReviewCurrent opinion in infectious diseases2020

Sapovirus: an emerging cause of childhood diarrhea.

Sylvia Becker-Dreps, Fredman González, Filemón Bucardo

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Sylvia Becker-DrepsDepartments of Family Medicine and Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Fredman GonzálezDepartment of Microbiology, National Autonomous University of Nicaragua, León, León, Nicaragua.
Filemón BucardoDepartment of Microbiology, National Autonomous University of Nicaragua, León, León, Nicaragua.
Universidad Nacional Autónoma de Nicaragua-León · NIUniversity of North Carolina at Chapel Hill · US

Funding

Natural history, immunity, and transmission patterns of sapovirus in a Nicaraguan birth cohortR01AI127845 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BECKER-DREPS, SYLVIA IRENE, VINJE, JAN · 2016 to 2020
$3.5M
Understanding protection against norovirus at the maternal-child interfaceK24AI141744 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Sylvia Irene Becker-Dreps · 2019 to 2026
$1.4M
Nicaraguan Emerging and Endemic Diseases (NEED) Training ProgramD43TW010923 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BECKER-DREPS, SYLVIA IRENE · 2018 to 2023
$1.4M
FIC NIH HHS D43 TW010923NIAID NIH HHS K24 AI141744NIAID NIH HHS R01 AI127845
6 · The paper itself

Abstract

purpose of reviewSapovirus, a genus in the Caliciviridae family alongside norovirus, is increasingly recognized as an important cause of childhood diarrhea. Some challenges exist in our ability to better understand sapovirus infections, including the inability to grow sapovirus in cell culture, which has hindered diagnosis and studies of immunity. Another challenge is that individuals with sapovirus infection are commonly coinfected with other enteric pathogens, complicating our ability to attribute the diarrhea episode to a single pathogen. RECENT

findingsDevelopment of molecular methods for sapovirus detection has increased our ability to measure disease prevalence. The prevalence of sapovirus varies between 1 and 17% of diarrhea episodes worldwide, with the highest burden in young children and older adults. Further, epidemiological studies have used novel approaches to account for the presence of coinfections with other enteric pathogens; one multisite cohort study of children under two years of age found that sapovirus had the second-highest attributable incidence among all diarrheal pathogens studied. SUMMARY: Especially in settings where rotavirus vaccines have been introduced, efforts to reduce the overall burden of childhood diarrhea should focus on the reduction of sapovirus transmission and disease burden.

Indexed as

AdolescentAdultAgedAged, 80 and overCaliciviridae InfectionsChildChild, PreschoolCohort StudiesCoinfectionDiarrheaFecesGastroenteritisGenetic VariationGenotypeHumansIncidenceRotavirus Vaccines

Identifiers

PMID32796163
PMCPMC7748384
OpenAlexW3049357037

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.