Evidence map›Paper›PMID 32795605›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2020

Nutritional status of patients with COVID-19.

Jae Hyoung Im, Young Soo Je, Jihyeon Baek, Moon-Hyun Chung, Hea Yoon Kwon, Jin-Soo Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers, 20 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
150citing papers in PubMed, 20 pooled it
34.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

150 citing papers in PubMed, 20 syntheses or guidelines pooled it, 270 citations in OpenAlex.

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  3. Gut distress and interventionFrontiers in public health · 2023
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  5. COVID-19 and Selenium Deficiency: a Systematic Review.Biological trace element research · 2022
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  15. Low vitamin D status is associated with coronavirus disease 2019 outcomes: a systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
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90 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jae Hyoung ImDivision of Infectious Diseases, Department of Internal Medicine, Inha University College of Medicine, Incheon, Republic of Korea.
Young Soo JeDepartment of Laboratory Medicine, Seoul Clinical Laboratories (SCL), Yongin, South Korea.
Jihyeon BaekDivision of Infectious Diseases, Department of Internal Medicine, Inha University College of Medicine, Incheon, Republic of Korea.
Moon-Hyun ChungThe Korean Society of Infectious Diseases, Republic of Korea.
Hea Yoon KwonDivision of Infectious Diseases, Department of Internal Medicine, Inha University College of Medicine, Incheon, Republic of Korea. Electronic address: haeyoon85@hanmail.net.
Jin-Soo LeeDivision of Infectious Diseases, Department of Internal Medicine, Inha University College of Medicine, Incheon, Republic of Korea. Electronic address: ljinsoo@inha.ac.kr.
Inha University · KRSeoul Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between immunity and nutrition is well known and its role in coronavirus disease 2019 (COVID-19) is also being paid great attention. However, the nutritional status of COVID-19 patients is unknown. Vitamin B1, B6, B12, vitamin D (25-hydroxyvitamin D), folate, selenium, and zinc levels were measured in 50 hospitalized patients with COVID-19. Overall, 76% of the patients were vitamin D deficient and 42% were selenium deficient. No significant increase in the incidence of deficiency was found for vitamins B1, B6, and B12, folate, and zinc in patients with COVID-19. The COVID-19 group showed significantly lower vitamin D values than the healthy control group (150 people, matched by age/sex). Severe vitamin D deficiency (based on a cut-off of ≤10 ng/dl) was found in 24.0% of the patients in the COVID-19 group and 7.3% in the control group. Among 12 patients with respiratory distress, 11 (91.7%) were deficient in at least one nutrient. However, patients without respiratory distress showed a deficiency in 30/38 cases (78.9%; p =  0.425). These results suggest that a deficiency of vitamin D or selenium may decrease the immune defenses against COVID-19 and cause progression to severe disease. However, more precise and large-scale studies are needed.

Indexed as

BetacoronavirusNutritional StatusAdultAgedCoronavirus InfectionsCOVID-19FemaleHumansMaleMiddle AgedPandemicsPneumonia, ViralSARS-CoV-2SeleniumVitamin D DeficiencyVitaminsSeleniumVitaminsZincCOVID-19SeleniumSevere acute respiratory syndrome coronavirus 2Vitamin DVitaminsZinc

Identifiers

PMID32795605
PMCPMC7418699
OpenAlexW3047725306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.