Evidence map›Paper›PMID 32795587›Full record

ArticleThe Journal of allergy and clinical immunology2020

Early epitope-specific IgE antibodies are predictive of childhood peanut allergy.

Maria Suprun, Scott H Sicherer, Robert A Wood, Stacie M Jones, Donald Y M Leung, Alice K Henning, Peter Dawson, A Wesley Burks, Robert Lindblad, Robert Getts and 2 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Epitope-Specific IgE at 1 Year of Age Can Predict Peanut Allergy Status at 5 Years.International archives of allergy and immunology · 2023
    Trial
  4. Trial
  5. Trial
  6. Review
  7. Wheat allergy, a new and emerging threat of food allergy for children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Feast for thought: A comprehensive review of food allergy 2021-2023.The Journal of allergy and clinical immunology · 2024
    Review
  13. CD23Science translational medicine · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Human Monoclonal IgE Antibodies-a Major Milestone in Allergy.Current allergy and asthma reports · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Maria SuprunIcahn School of Medicine at Mount Sinai, New York, NY.
Scott H SichererIcahn School of Medicine at Mount Sinai, New York, NY.
Robert A WoodJohns Hopkins University School of Medicine, Baltimore, Md.
Stacie M JonesUniversity of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock, Ark.
Donald Y M LeungNational Jewish Health, Denver, Colo.
Alice K HenningEmmes, Rockville, Md.
Peter DawsonEmmes, Rockville, Md.
A Wesley BurksUniversity of North Carolina, Chapel Hill, NC.
Robert LindbladEmmes, Rockville, Md.
Robert GettsAllerGenis LLC, Hatfield, Pa.
Mayte Suárez-FariñasIcahn School of Medicine at Mount Sinai, New York, NY.
Hugh A SampsonIcahn School of Medicine at Mount Sinai, New York, NY. Electronic address: hugh.sampson@mssm.edu.
Icahn School of Medicine at Mount Sinai · USEmmes (United States) · USArkansas Children's Hospital · USJohns Hopkins University · USNational Jewish Health · USUniversity of North Carolina at Chapel Hill · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Mechanistic CoreU19AI066738 · NIAID · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SAMPSON, HUGH A · 2005 to 2016
$43.6M
Expanding Translational Research in ArkansasUL1TR003107 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2019 to 2023
$21.6M
Mount Sinai Institutes for Clinical and Translational SciencesUL1TR000067 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SAMPSON, HUGH A · 2012 to 2014
$16.5M
Food Allergy Research Consortium and Statistical CenterU01AI066560 · NIAID · THE EMMES COMPANY, LLC · PI DAWSON, PETER RUSSELL, LINDBLAD, ROBERT · 2005 to 2016
$12.8M
UNC Clinical and Translational Science AwardUL1TR000083 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2012 to 2013
$11.6M
Teaching biomedical and pharmacological trainees to produce FAIR data for AI & ML applicationsT32GM062754 · NIGMS · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SCHLESSINGER, AVNER · 2001 to 2023
$6.2M
Institute for Clinical and Translational ResearchUL1TR000424 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2012 to 2012
$6.0M
Arkansas Center for Food Allergy Research (ArCOFAR)UM1AI130781 · NIAID · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI JONES, STACIE M · 2017 to 2023
$1.6M
NCATS NIH HHS UL1 TR000067NCATS NIH HHS UL1 TR000083NCATS NIH HHS UL1 TR000424NCATS NIH HHS UL1 TR002535NCATS NIH HHS UL1 TR003107NIAID NIH HHS U01 AI066560NIAID NIH HHS U19 AI066738NIAID NIH HHS UM1 AI130781NIGMS NIH HHS T32 GM062754
6 · The paper itself

Abstract

backgroundPeanut allergy is characterized by the development of IgE against peanut antigen.

objectiveWe sought to evaluate the evolution of epitope-specific (es)IgE and esIgG

methodsThe end point was allergy status at age 4

resultsAt age 4

conclusionsEarly epitope-specific plus peanut-specific IgE is predictive of allergy status at age 4

Indexed as

AdolescentAlgorithmsAllergensArachisChildChild, PreschoolCohort StudiesEpitopesFemaleFollow-Up StudiesHumansImmune ToleranceImmunoglobulin EImmunoglobulin GInfantMachine LearningAllergensEpitopesImmunoglobulin EImmunoglobulin GantibodiesAra h 1Ara h 2Ara h 3Bead-Based Epitope AssayepitopesIgEIgG(4)machine learningPeanut allergyprecision medicine

Identifiers

PMID32795587
PMCPMC8095129
OpenAlexW3048667874

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.