ArticleThe Journal of infection2021
Circulating levels of GDF-15 and calprotectin for prediction of in-hospital mortality in COVID-19 patients: A case series.
Registry-linked trialOpen access · bronzeAbstract readLetterComment
In one paragraph
Article in The Journal of infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04953312 (Calprotectin Involvement in Emergency Hematopoiesis Observed in Severe COVID-19), which is not on this map. Cited by 45 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
9.1field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Calprotectin Involvement in Emergency Hematopoiesis Observed in Severe COVID-19
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Elevated level of circulating calprotectin correlates with severity and high mortality in patients with COVID-19.Immunity, inflammation and disease · 2024Pooled it
- Organokines in COVID-19: A Systematic Review.Cells · 2023Pooled it
- Complement system component dysregulation is a distinctive feature of COVID-19 disease: a prospective and comparative analysis of patients admitted to the emergency department for suspected COVID-19 disease.Journal of thrombosis and thrombolysis · 2022Trial
- Article
- Multi-omics analysis of long COVID (post-COVID-19 condition) reveals persistent mitochondrial dysfunction, suppressed oxidative phosphorylation, and immune dysregulation.Frontiers in immunology · 2026Article
- Blood calprotectin as a biomarker for infection and sepsis - the prospective CASCADE trial.BMC infectious diseases · 2024Observational
- GDF-15 Levels and Other Laboratory Findings as Predictors of COVID-19 Severity and Mortality: A Pilot Study.Biomedicines · 2024Article
- Proteomics validate circulating GDF-15 as an independent biomarker for COVID-19 severity.Frontiers in immunology · 2024Article
- Serum growth differentiation factor-15 (GDF-15) is a biomarker of cardiac manifestations in children with COVID-19.European journal of medical research · 2023Article
- Elevated Level of Circulating but Not Urine S100A8/A9 Identifies Poor COVID-19 Outcomes.ACS infectious diseases · 2023Article
- Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts.Science translational medicine · 2023Article
- Cardiac Biomarkers and Their Role in Identifying Increased Risk of Cardiovascular Complications in COVID-19 Patients.Diagnostics (Basel, Switzerland) · 2023Review
- Pilot study to evaluate hypercoagulation and inflammation using rotational thromboelastometry and calprotectin in COVID-19 patients.PloS one · 2023Article
- The Cytokine Growth Differentiation Factor-15 and Skeletal Muscle Health: Portrait of an Emerging Widely Applicable Disease Biomarker.International journal of molecular sciences · 2022Review
- Calprotectin Levels and Neutrophil Count Are Prognostic Markers of Mortality in COVID-19 Patients.Diagnostics (Basel, Switzerland) · 2022Article
- Growth differentiation factor 15 as an emerging novel biomarker in SARS-CoV-2 infection.World journal of methodology · 2022Article
- The Potential Role of Growth Differentiation Factor 15 in COVID-19: A Corollary Subjective Effect or Not?Diagnostics (Basel, Switzerland) · 2022Review
- Role of cystatin C and calprotectin as potential early prognostic biomarkers in COVID-19 patients admitted to a dedicated COVID care facility.Journal of family medicine and primary care · 2022Article
- Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 Thrombosis Biomarkers Colloquium.Nature reviews. Cardiology · 2022Review
- Review
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Authors and funding
13 authors at 2 institutions in 1 country.
Luis García de Guadiana RomualdoMedicine Laboratory Department, Hospital Universitario Santa Lucía, Cartagena, Spain. C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain. Electronic address: guadianarom@yahoo.es.
María Dolores Rodríguez MuleroIntensive Care Unit, Hospital Universitario Santa Lucía, Cartagena, Spain. C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Marta Hernández OlivoPneumology Department, Hospital Universitario Santa Lucía, Cartagena, Spain C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Carlos Rodríguez RojasMedicine Laboratory Department, Hospital Universitario Santa Lucía, Cartagena, Spain. C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Verónica Ramos ArenasMedicine Laboratory Department, Hospital Universitario Santa Lucía, Cartagena, Spain. C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Mercedes González MoralesMedicine Laboratory Department, Hospital Universitario Santa Lucía, Cartagena, Spain. C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Ana Blazquez AbellánMicrobiology and Parasitology Department, Hospital Universitario Santa Lucía, Cartagena, Spain. C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Pablo Conesa-ZamoraMedicine Laboratory Department, Hospital Universitario Santa Lucía, Cartagena, Spain. C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Josefina García-GarcíaInfectious Diseases Unit, Internal Medicine Department, Hospital Universitario Santa Lucía, Cartagena, Spain. C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Andrés Conesa HernándezEmergency Department ,Hospital Universitario Santa Lucía, Cartagena, Spain. C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Daniel Morell-GarcíaMedicine Laboratory Department, Hospital Universitario Son Espases, Palma de Mallorca, Spain. Carretera de Valldemossa 79, Palma 07120, Spain.
María Dolores Albaladejo-OtónMedicine Laboratory Department, Hospital Universitario Santa Lucía, Cartagena, Spain. C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Luciano Consuegra-SánchezCardiology Department, Hospital Universitario Santa Lucía, Cartagena, Spain C/ Mezquita, s/n, Paraje Los Arcos, Cartagena, Santa Lucía 30202, Spain.
Santa Lucía University General Hospital · ESHospital Universitario Son Espases · ES
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
CoronavirusCOVID-19BiomarkersGrowth Differentiation Factor 15Hospital MortalityHumansLeukocyte L1 Antigen ComplexPrognosisSARS-CoV-2Serum Amyloid A ProteinBiomarkersGrowth Differentiation Factor 15Leukocyte L1 Antigen ComplexSerum Amyloid A ProteinCalprotectinCOVID-19GDF-15Prognosis
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT04953312ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.