Evidence map›Paper›PMID 32795477›Full record

ArticleThe Journal of pediatrics2020

Relationship of Apolipoproteins with Subclinical Cardiovascular Risk in Youth.

Madeline A Czeck, Elise F Northrop, Nicholas G Evanoff, Donald R Dengel, Kyle D Rudser, Aaron S Kelly, Justin R Ryder

Open access · greenAbstract read
In one paragraph

Article in The Journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Madeline A CzeckSchool of Kinesiology, University of Minnesota, Minneapolis, MN. Electronic address: czeck010@umn.edu.
Elise F NorthropDivision of Biostatistics, University of Minnesota, Minneapolis, MN.
Nicholas G EvanoffSchool of Kinesiology, University of Minnesota, Minneapolis, MN; Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN.
Donald R DengelSchool of Kinesiology, University of Minnesota, Minneapolis, MN; Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN.
Kyle D RudserDivision of Biostatistics, University of Minnesota, Minneapolis, MN; Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN.
Aaron S KellyCenter for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN.
Justin R RyderCenter for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, MN; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN.
University of Minnesota · USUniversity of Minnesota Medical Center · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
UNIVERSITY OF MINNESOTA CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE (UMN CTSI)UL1RR033183 · NCRR · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2011 to 2011
$8.9M
Validation of Circulating Endothelial Cells and Microparticles in YouthR01HL110957 · NHLBI · UNIVERSITY OF MINNESOTA · PI KELLY, AARON S · 2012 to 2016
$3.2M
Longitudinal assessment of novel biomarkers for predicting cardiovascular disease in youthF32HL127851 · NHLBI · UNIVERSITY OF MINNESOTA · PI RYDER, JUSTIN R. · 2015 to 2016
$61k
NCATS NIH HHS UL1 TR000114NCATS NIH HHS UL1 TR002494NCRR NIH HHS UL1 RR033183NHLBI NIH HHS F32 HL127851NHLBI NIH HHS R01 HL110957
6 · The paper itself

Abstract

objectiveTo examine the association of apolipoproteins with arterial stiffness and carotid artery structure in children and adolescents. STUDY

designA total of 338 children and adolescents (178 female) with a mean age 13.0 ± 2.8 years were examined. Apolipoproteins (AI, AII, B

resultsThere was a significant positive association between pulse wave velocity and apolipoproteins: AI (0.015 m/s/10 μg/mL [CI 0.005-0.026], P = .003), AII (0.036 m/s/10 μg/mL [0.017-0.056], P < .001), B

conclusionsThese findings suggest that greater levels of apolipoprotein AII, E, and CIII:CII are associated with increased arterial stiffness in children and adolescents, both with and without adjusting for percent body fat. These specific apolipoproteins may be useful as biomarkers of cardiovascular risk.

Indexed as

Carotid Intima-Media ThicknessVascular StiffnessAdolescentApolipoproteinsCardiovascular DiseasesChildFemaleHumansMalePulse Wave AnalysisRisk AssessmentUltrasonography, InterventionalApolipoproteinsarterial stiffnessarterial structurecarotid intima-media thicknesspediatricspulse wave velocity

Identifiers

PMID32795477
PMCPMC7686115
OpenAlexW3048555038

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.