ArticleCurrent biology : CB2020
Identification of the First Oomycete Mating-type Locus Sequence in the Grapevine Downy Mildew Pathogen, Plasmopara viticola.
Article in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- Multivirulent Plasmopara viticola strains from Cilaos on Réunion Island break down Rpv1, Rpv3.1 and Rpv10 mediated resistance of grapevine.BMC plant biology · 2026Article
- Phylogenomics of Plasmopara halstedii Reveals Genomic Regions Associated With the Breakdown of Sunflower Downy Mildew Resistance Genes.Molecular ecology · 2026Article
- Rethinking grapevine downy mildew management: opportunities to disrupt the sexual cycle of the pathogen as a preventive disease control strategy.Frontiers in plant science · 2026Article
- k-mer-based GWAS reveals a candidate avirulence gene and structural variation in Puccinia triticina linked to gain of Lr20 virulence.BMC genomics · 2025Article
- The role of selection pressure in shaping zoxamide resistance in Plasmopara viticola populations.Pest management science · 2025Article
- An Inversion Polymorphism Under Balancing Selection, Involving Giant Mobile Elements, in an Invasive Fungal Pathogen.Molecular biology and evolution · 2025Article
- Recombination landscape and karyotypic variations revealed by linkage mapping in the grapevine downy mildew pathogen Plasmopara viticola.G3 (Bethesda, Md.) · 2025Article
- Optimizing a modified cetyltrimethylammonium bromide protocol for fungal DNA extraction: Insights from multilocus gene amplification.Open life sciences · 2025Article
- Origin and pathogenicity variation ofFrontiers in microbiology · 2024Article
- Propensity for selfing varies within a population of hermaphroditic snails: coexistence of selfers, outcrossers and mixed-mating individuals.Royal Society open science · 2023Article
- Phylogeography and population structure of the global, wide host-range hybrid pathogen Phytophthora × cambivora.IMA fungus · 2023Article
- Pathogen Adaptation to American (Plants (Basel, Switzerland) · 2022Article
- Diploid-dominant life cycles characterize the early evolution of Fungi.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- The mysterious route of sterols in oomycetes.PLoS pathogens · 2021Review
- Recombination suppression and evolutionary strata around mating-type loci in fungi: documenting patterns and understanding evolutionary and mechanistic causes.The New phytologist · 2021Review
- SMARTdenovo: aGigaByte (Hong Kong, China) · 2021Article
- The Study of the Germination Dynamics ofFrontiers in microbiology · 2021Article
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
Mating types are self-incompatibility systems that promote outcrossing in plants, fungi, and oomycetes. Mating-type genes have been widely studied in plants and fungi but have yet to be identified in oomycetes, eukaryotic organisms closely related to brown algae that cause many destructive animal and plant diseases. We identified the mating-type locus of Plasmopara viticola, the oomycete responsible for grapevine downy mildew, one of the most damaging grapevine diseases worldwide. Using a genome-wide association approach, we identified a 570-kb repeat-rich non-recombining region controlling mating types, with two highly divergent alleles. We showed that one mating type was homozygous, whereas the other was heterozygous at this locus. The mating-type locus encompassed 40 genes, including one encoding a putative hormone receptor. Functional studies will, however, be required to validate the function of these genes and find the actual determinants of mating type. Our findings have fundamental implications for our understanding of the evolution of mating types, as they reveal a unique determinism involving an asymmetry of heterozygosity, as in sex chromosomes and unlike other mating-type systems. This identification of the mating-type locus in such an economically important crop pathogen also has applied implications, as outcrossing facilitates rapid evolution and resistance to harsh environmental conditions.
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