Evidence map›Paper›PMID 32795352›Full record

Observational studyBMC medical informatics and decision making2020

WEARCON: wearable home monitoring in children with asthma reveals a strong association with hospital based assessment of asthma control.

M R van der Kamp, E C Klaver, B J Thio, J M M Driessen, F H C de Jongh, M Tabak, J van der Palen, H J Hermens

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC medical informatics and decision making, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 53 citations in OpenAlex.

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  19. Volatile organic breath components and exercise induced bronchoconstriction in asthmatic children.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

M R van der KampDepartment of Paediatrics, Medisch Spectrum Twente, Enschede, Netherlands. mattienne@gmail.com.
E C KlaverDepartment of Paediatrics, Medisch Spectrum Twente, Enschede, Netherlands.
B J ThioDepartment of Paediatrics, Medisch Spectrum Twente, Enschede, Netherlands.
J M M DriessenOCON sport, Hengelo, Netherlands.
F H C de JonghDepartment of Pulmonology, Medisch Spectrum Twente, Enschede, Netherlands.
M TabakDepartment of Biomedical Signals and Systems, University of Twente, Enschede, Netherlands.
J van der PalenMedical School Twente, Medisch Spectrum Twente, Enschede, Netherlands.
H J HermensDepartment of Biomedical Signals and Systems, University of Twente, Enschede, Netherlands.
University of Twente · NLMedisch Spectrum Twente · NLRoessingh Research and Development · NLOCON Orthopedische kliniek · NL

Funding

Stichting Pediatrisch Onderzoek Enschede (NL) n.a. unrestricted grant
6 · The paper itself

Abstract

backgroundAsthma is one of the most common chronic diseases in childhood. Regular follow-up of physiological parameters in the home setting, in relation to asthma symptoms, can provide complementary quantitative insights into the dynamics of the asthma status. Despite considerable interest in asthma home-monitoring in children, there is a paucity of scientific evidence, especially on multi-parameter monitoring approaches. Therefore, the aim of this study is to investigate whether asthma control can be accurately assessed in the home situation by combining parameters from respiratory physiology sensors.

methodsSixty asthmatic and thirty non-asthmatic children were enrolled in the observational WEARCON-study. Asthma control was assessed according to GINA guidelines by the paediatrician. All children were also evaluated during a 2-week home-monitoring period with wearable devices; a physical activity tracker, a handheld spirometer, smart inhalers, and an ambulatory electrocardiography device to monitor heart and respiratory rate. Multiple logistic regression analysis was used to determine which diagnostic measures were associated with asthma control.

results24 of the 27 uncontrolled asthmatic children and 29 of the 32 controlled asthmatic children could be accurately identified with this model. The final model showed that a larger variation in pre-exercise lung function (OR = 1.34 95%-CI 1.07-1.68), an earlier wake-up-time (OR = 1.05 95%-CI 1.01-1.10), more reliever use (OR = 1.11 95%-CI 1.03-1.19) and a longer respiratory rate recovery time (OR = 1.12 95%-CI 1.05-1.20) were significant contributors to the probability of having uncontrolled asthma.

conclusionsHome-monitoring of physiological parameters correlates with paediatrician assessed asthma control. The constructed multivariate model identifies 88.9% of all uncontrolled asthmatic children, indicating a high potential for monitoring of asthma control. This may allow healthcare professionals to assess asthma control at home.

trial registrationNetherlands Trail Register, NL6087 . Registered 14 February 2017.

Indexed as

Fitness TrackersAsthmaCase-Control StudiesChildExerciseFemaleHumansMaleMonitoring, AmbulatoryNetherlandsSpirometryAmbulatory monitoringAsthma controleHealthInhaler useMultivariate analysisPaediatricsPhysiology sensorsspirometryTelemedicineWearable electronic devices

Identifiers

PMID32795352
PMCPMC7427745
OpenAlexW3049239500

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.