ArticleCancer imaging : the official publication of the International Cancer Imaging Society2020
Primary hepatic malignant vascular tumors: a follow-up study of imaging characteristics and clinicopathological features.
Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 14 citations in OpenAlex.
- An AI-Assisted Protocol for Quantifying Superficial Chorioallantoic Membrane Vasculature.Cells, tissues, organs · 2026Article
- Magnetic resonance imaging and clinicopathological findings of primary hepatic angiosarcoma.Abdominal radiology (New York) · 2025Article
- Comparison of clinical and MRI features of hepatic angiosarcoma and epithelioid hemangioendothelioma.Abdominal radiology (New York) · 2025Article
- Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review.International journal of women's health · 2025Article
- [MRI manifestations of 40 cases with the hepatic epithelioid hemangioendothelioma classification based on the morphology and size].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024Article
- Proposed diagnostic and prognostic markers of primary malignant hepatic vascular neoplasms.Diagnostic pathology · 2024Article
- Review
- Characteristic contrast‑enhanced ultrasound findings of hepatic epithelioid haemangioendothelioma: A case report and literature review.Oncology letters · 2023Article
- A complementary comment on primary hepatic angiosarcoma: A case report.World journal of clinical cases · 2023Article
- Primary hepatic angiosarcoma: A case report.World journal of clinical cases · 2022Article
- Magnetic Resonance Imaging and Serum AFP-L3 and GP-73 in the Diagnosis of Primary Liver Cancer.Journal of oncology · 2022Article
- Establishment and validation of prognostic nomograms to predict the overall and cancer-specific survival in patients with hepatic malignant vascular tumors.American journal of translational research · 2022Article
- Hepatic Epithelioid Hemangioendothelioma Presenting Synchronously with Hepatocellular Carcinoma.Case reports in gastroenterologyArticle
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5 authors at 1 institution in 1 country.
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Abstract
backgroundOwing to its low incidence, there is insufficient clinical awareness and diagnostic experience with primary hepatic malignant vascular tumors (PHMVTs). The aim of our study was to investigate the imaging and clinicopathological features of patients with PHMVTs and analyze the clinicopathological correlations.
methodsWe retrospectively analyzed 42 patients who had pathologically confirmed PHMVT during the period from June 2012 to December 2019 and enrolled them in our study. The computed tomography (CT) and magnetic resonance (MR) images and pathological findings of each patient were recorded.
resultsThere were more female (29/42) than male patients. The imaging features of primary hepatic angiosarcoma (PHA) (n = 11) included ill-defined margins (11/11, 100%), necrosis (5/11, 45%), calcification (3/11, 27%) and "slow in-slow out" centripetal enhancement (7/11, 64%). Patients with epithelioid hemangioendothelioma (EHE) (n = 15) presented with ill-defined margins (15/15, 100%), necrosis (6/15, 40%), calcification (2/15, 13%), "fast in-slow out" centripetal enhancement (10/15, 67%), halo sign (15/15, 100%), pseudocapsule sign (4/15, 27%), lollipop sign (2/15, 13%) and capsule retraction sign (2/15, 13%). Patients with malignant hemangiopericytoma (MHP) (n = 3) showed ill-defined margins (3/3, 100%), necrosis (3/3, 100%) and "fast in-slow out" progressive enhancement (3/3, 100%). Infantile hemangioendotheliomas (IHEs) (n = 13) were defined by ill-defined margins (7/13, 54%), necrosis (8/13, 62%), calcification (5/13, 38%) and "fast in-slow out" centripetal enhancement (13/13, 100%). Immunohistochemistry showed strong positive expression of CD31, CD34, ERG, FaVIII and FLI-1. Patients with IHE (96 months) and EHE (88 months) had the longest survival times, followed by those with MHP (23 months), while patients with PHA (15 months) had the shortest survival time.
conclusionOn CT and MR images, most PHMVTs were ill-defined, heterogeneous, hypervascular masses with centripetal progressive enhancement and possibly calcification, especially in female patients. The prognosis of patients with PHMVT was associated with the pathological type of the tumor.
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