Evidence map›Paper›PMID 32794638›Full record

ArticleCancer reports (Hoboken, N.J.)2020

Accurate likelihood inference for the volume under the ROC surface.

Erlis Ruli, Laura Ventura

Abstract read
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

2 authors.

Erlis RuliDepartment of Statistical Sciences, University of Padua, Padua, Italy.ORCID 0000-0001-8572-2149
Laura VenturaDepartment of Statistical Sciences, University of Padua, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith three ordered diagnostic categories, the volume under the receiver operating characteristic (ROC) surface, which is the extension of the area under the ROC curve for binary diagnostic outcomes, is the most commonly used measure for the overall diagnostic accuracy. For a continuous-scale diagnostic test, classical likelihood-based inference about the area under the ROC curve can be inaccurate, in particular when the sample size is small, and higher order inferential procedures have been proposed.

aimThe goal of this paper is to illustrate higher order likelihood procedures for parametric inference in small samples, which provide accurate point estimates and confidence intervals for the volume under the ROC surface.

methodsSimulation studies are performed in order to illustrate the accuracy of the proposed methodology, and two applications to real data are discussed.

resultsWe show that likelihood modern inference provide refinements to classical inferential results. Furthermore, the freely available R package likelihoodAsy makes now their use almost automatic.

conclusionModern likelihood inference based on higher-order asymptotic methods for the area under the ROC surface provide refinements to classical inferential results. A possible limitation of higher-order asymptotic methods for practical use is that their software implementation can be awkward. Nevertheless, use of the freely available R package likelihoodAsy makes such implementation straightforward.

Indexed as

Likelihood FunctionsROC CurveComputer SimulationDiagnostic Tests, RoutineHumansAUCdiagnostic accuracyhigher order likelihood inferencesmall sample sizestress-strength modelVUS

Identifiers

PMID32794638
PMCPMC7941487

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.