Evidence map›Paper›PMID 32794615›Full record

ArticleJournal of veterinary internal medicine2020

Long-term clinical and magnetic resonance imaging follow-up of dogs with osseous-associated cervical spondylomyelopathy.

Carolyn Nye, Eric Hostnik, Elizabeth Parker, Thomas Wittum, Stephen Jones, Sarah Moore, Laurie Cook, Ronaldo C da Costa

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Carolyn NyeDepartment of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0003-3412-2260
Eric HostnikDepartment of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-7651-4775
Elizabeth ParkerDepartment of Animal Sciences, The Ohio State University, Columbus, Ohio, USA.
Thomas WittumDepartment of Veterinary Preventative Medicine, The Ohio State University, Columbus, Ohio, USA.
Stephen JonesDepartment of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-5515-8644
Sarah MooreDepartment of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-4311-6199
Laurie CookDepartment of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, USA.
Ronaldo C da CostaDepartment of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, USA.
The Ohio State University · US

Funding

Gray Lady Foundation
6 · The paper itself

Abstract

backgroundOsseous-associated cervical spondylomyelopathy (OA-CSM) is a complex disorder with limited long-term survival. The longitudinal progression is currently unknown.

objectiveTo describe changes on magnetic resonance imaging (MRI) over a 2-year minimum period. We hypothesized that spinal lesions would progress in the majority of dogs. ANIMALS: Eleven dogs previously diagnosed with OA-CSM were prospectively studied. Nine dogs were treated medically, whereas 2 were treated surgically.

methodsClinical and MRI follow-up were performed with a median time between MRI studies of 30 months (range, 24-54). Morphologic assessment evaluated vertebral canal stenosis, spinal cord compression, foraminal stenosis, and articular processes, among other variables. Morphometric assessment included vertebral canal area, spinal cord area, area of the articular processes, and foraminal height.

resultsOn follow-up MRI, the most affected site at the initial examination in medically treated dogs had progressed in 4 of 9 dogs, improved in 4, and was unchanged in 3. Clinically, all dogs except 2 medically treated dogs were unchanged to improve at follow-up. Initially, 50 of 60 (83.3%) intervertebral spaces had vertebral canal stenosis, whereas in the follow-up MRI 82.3% did. Of the sites with stenosis, 45.7% were unchanged, 18.6% improved, and 38.9% worsened. Morphometry identified significant decreases in vertebral canal and spinal cord areas at C4-C5 through C6-C7, and significant progression of articular process irregularities at C3-C4 and C6-C7. CONCLUSIONS AND CLINICAL IMPORTANCE: This long-term follow-up study of dogs with OA-CSM did not identify clinical or MRI progression of lesions in the majority of dogs.

Indexed as

Dog DiseasesSpinal Cord CompressionSpinal StenosisAnimalsCervical VertebraeDogsFollow-Up StudiesMagnetic Resonance Imagingarticular facetlongitudinal studymyelopathynatural historyspinal cordwobbler syndrome

Identifiers

PMID32794615
PMCPMC7517862
OpenAlexW3049037880

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.