Evidence map›Paper›PMID 32794120›Full record

ArticleEuropean journal of pediatrics2020

Echocardiographic assessment of hemodynamic changes in preterm neonates with shock: a prospective pragmatic cohort study.

Dinesh Pawale, Srinivas Murki, Dattatray Kulkarni, Venkateshwarlu Vardhelli, Deepak Sharma, Tejopratap Oleti, Sai Kiran, Shweta Bakhru, Nageswar Rao Koneti

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Article in European journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Integration of inferior vena cava measurements into routine functional echocardiography in preterm neonates. Are We There Yet?Journal of perinatology : official journal of the California Perinatal Association · 2025
    Observational
  4. Observational
  5. [Value of functional echocardiographic parameters in predicting refractory septic shock in neonates].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dinesh PawaleFernandez Hospital, Hyderabad, India. dinesh_pawale@rediffmail.com.ORCID http://orcid.org/0000-0001-7876-6936
Srinivas MurkiFernandez Hospital, Hyderabad, India.
Dattatray KulkarniFernandez Hospital, Hyderabad, India.
Venkateshwarlu VardhelliFernandez Hospital, Hyderabad, India.
Deepak SharmaFernandez Hospital, Hyderabad, India.
Tejopratap OletiFernandez Hospital, Hyderabad, India.
Sai KiranFernandez Hospital, Hyderabad, India.
Shweta BakhruRainbow Children's Heart Institute, Hyderabad, India.
Nageswar Rao KonetiRainbow Children's Heart Institute, Hyderabad, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shock is a state of circulatory dysfunction and its diagnosis is complex in neonates. Hemodynamic assessment using echocardiography has potential to guide better management regimes in neonates with shock. Objective of this study is to analyze changes in the echocardiographic parameters in preterm neonates with shock at presentation and after resolution. In this prospective pragmatic Cohort study, eligible neonates with shock were monitored for changes in echocardiographic parameters at onset of shock and after resolution of shock. Paired data analysis was done for observed changes in the parameters. Based on initial clinical parameters and echocardiographic parameters, infants were assigned into different types of shock. Data of 37 infants were analyzed for baseline clinical and echocardiographic parameters, and data of 31 infants were analyzed for the changes in the observed parameters after shock resolution. Statistically significant changes were observed in inferior vena cava collapsibility index (ICI), left ventricular end diastolic volume (LVEDV), isovolemic ventricular relaxation time (IVRT), left and right ventricular stroke volume, and ejection fraction (EF). There was no agreement between clinical and echocardiographic definitions of shock.Conclusion: We noticed shock has overlapping pathophysiologic features. Our study highlights the importance of baseline documentation of echocardiographic parameters of all infants who are at risk of shock and repeat echocardiography at onset of shock to observe the changes in ICI, LVEDV, IVRT, stroke volume, and EF. This would guide pathophysiological management of shock in neonates. What is Known: • In neonates pathophysiology of shock is overlapping. • Echocardiography can help in better understanding and management of shock. What is New: • Study gives median changes in major echocardiographic parameters in neonatal shock. • These changes can guide for selection of volume and inotropes in management.

Indexed as

EchocardiographyHemodynamicsShockCohort StudiesHumansInfantInfant, NewbornProspective StudiesStroke VolumeCardiac outputEchocardiographyHemodynamicIVC collapsibility indexNeonatal shock

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.